Hello, I research pharmacokinetics and pharmcodynamics of various phytochemicals, drugs, etc. What is your goal? And what info would you like on carbon60

edit after some preliminary research

• Mechanism of Action:

  • Acts as a powerful antioxidant, scavenging free radicals and reducing oxidative stress.
  • May reduce inflammation by downregulating pro-inflammatory cytokines.
  • Demonstrates potential neuroprotective effects, crossing the blood-brain barrier.

• Pharmacokinetics:

  • Enhanced bioavailability when dissolved in oils (e.g., olive, coconut, avocado oil).
  • Absorbed in the gastrointestinal tract; distributed throughout the body.
  • Primarily excreted through fecal matter, with limited bioaccumulation.
  • Long half-life and stable structure suggest prolonged biological activity.

• Safety Profile:

  • Low acute toxicity in preclinical studies, especially in oil-based forms.
  • No significant hepatotoxicity, nephrotoxicity, or blood alterations in animal models.
  • Minimizes phototoxicity risk when stored away from UV light.

• Potential Benefits:

  • Antioxidant: Reduces oxidative damage to cells, proteins, and DNA.
  • Anti-inflammatory: May alleviate chronic inflammation in conditions like arthritis and cardiovascular disease.
  • Neuroprotection: Potential protection against neurodegenerative diseases (e.g., Alzheimer's, Parkinson's).
  • Anti-aging: Hypothesized to reduce cellular aging through free radical scavenging.

• Clinical Use Considerations:

  • Oil-based formulations recommended for enhanced absorption; olive oil-based C60 is the most studied.
  • May be beneficial for patients with oxidative stress or inflammatory conditions.
  • Caution advised in patients with pre-existing liver or kidney conditions.
  • Monitor for interactions with other pharmaceutical agents and potential phototoxicity.