Syncopes, paresis & loss of vision after COVID-19 mRNA-based vaccination & SARS-CoV-2 infection

👉🏻 https://link.springer.com/article/10.1007/s15010-024-02439-y

• "6 h after vaccination, the patient developed severe cephalgia & dizziness lasting for several days"
• "Spontaneous syncope occurred 20–30 times over the following 2 weeks. Even though the syncopes disappeared, the patient continued to observe irregular heartbeats. ... he reported new onset of fatigue, brain fog, acral paresthesia, paresis of forearm extensors and Mm. quadriceps femoris, disseminated fasciculations & urticaria in the weeks following the vaccination"
• "143 days after vaccination, the patient suffered a PCR confirmed SARS-CoV-2 infection, and the symptoms experienced after vaccination exacerbated"
• "The details on the mechanisms underlying adverse side effects caused by mRNA-based vaccines remain unclear"
• "Further mechanistic research assessing the pathologies that may trigger mRNA vaccine-associated symptoms are urgently needed"

👉🏻 https://link.springer.com/article/10.1007/s12026-024-09553-x#Sec7

"The vaccines imposed severe potential health side effects such as clotting or obstruction of blood vessels termed arterial or venous thrombosis, autoimmune damage of nerve cells (Guillain-Barré syndrome; GBS), intense activation of coagulation system (vaccine-induced thrombotic thrombocytopenia), acute ischemic stroke (AIS) and cerebral venous sinus thrombosis (CVST), myocarditis, pericarditis, and glomerular disease."

• "It is essential to continue rigorous follow-up and surveillance studies to monitor vaccine safety and identify potential risks, particularly in immunocompromised individuals, those with comorbidities, and other vulnerable populations."
• "Long-term data on vaccine interactions, effects during pregnancy, and implications for individuals with autoimmune or inflammatory conditions are still needed."

Optic neuritis & short-segment myelitis following ChAdOx1 adenovirus COVID-19 vaccination

👉🏻 https://journals.lww.com/neur/fulltext/2024/11000/optic_neuritis_and_short_segment_myelitis.28.aspx

• "Magnetic resonance imaging of the brain showed T2/FLAIR hyperintensity of the right optic nerve. The middle portion of the right optic nerve showed mild enhancement."
• "MRI of the spinal cord demonstrated a short-segment T2/FLAIR hyperintensity in the cervicothoracic region" (-> small vessel spinal cord strokes)

Kounis syndrome following COVID-19 vaccination

👉🏻 https://www.tandfonline.com/doi/10.1080/21645515.2024.2365496?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed#abstract

Kounis syndrome: "an acute coronary syndrome triggered by allergic mediators that induce coronary vasoconstriction and thrombosis, leading to further myocardial damage and anaphylactic shock."

• "Most patients developed clinical manifestations associated with Kounis syndrome within 2 hours of vaccination and progressed rapidly."

SARS-CoV-2 vaccine-associated liver injury (SVALI)

👉🏻 https://onlinelibrary.wiley.com/doi/10.1111/liv.16209

• "The heterogeneous clinical entity of acute liver injury linked to SARS-CoV-2 vaccines includes patients requiring long-term immunosuppression, similarly to autoimmune hepatitis, and patients with self-limiting liver damage, possibly representing a unique form of autoimmune-like hepatitis, which we suggest being referred to as SARS-CoV-2 vaccine-associated liver injury (SVALI)."
• "Further studies are needed to investigate the pathogenic mechanisms related to the immune response to the spike viral protein in the liver."

New study

Changing epidemiology of myocarditis in Australia: A population-nased cohort study

👉🏻 https://www.mdpi.com/2077-0383/13/23/7111

Analyzed data: 2001-2022

"There was an inflexion point in 2021 during which the growth rate in the incidence of myocarditis accelerated. By 2022, the incidence of myocarditis was about 8 cases per-100,000 with no sign of slowing."

"The current study underlines the rising incidence of myocarditis, especially post-pandemic."

I am wondering about this sharp increase in cases of myocarditis. What could be the reason? Any ideas? ...