Thank you. Well said. Please post your thoughts on the clinical trials process. Often, trials are farmed out to “favorite” third parties to conduct. If the company, in this case Pfizer, is happy with the results then more clinical trials go their way. If they aren’t happy, it goes elsewhere next time. So in order to keep those multi million trials coming their way, those third parties know how to construct and engineer the trials to increase the odds for a favorable response.
Then the reports are written and submitted to the medical journals that are bloated with full page ads from these same drug companies. Without the ad revenue the journals cease to exist. So the editorial board considers which studies to include and which to reject. Is it any wonder that the only ones that see the light of day are those that find the drugs are well tolerated, show positive results, should be approved, etc?
The whole dam system is corrupt end to end IMHO. I’d love to read your thoughts.
Thank you. You seem to have a pretty good handle on how the whole process works and you hit the nails on their heads. I don't have much to add to what you so well summarized. Your conclusions are right on the money - pun intended.
The whole process was very frustrating and disheartening when I worked in research and later, clinical practice. What science should be researched for the good of humanity is sidelined for profit. If there is no pot of gold at the end of that rainbow there is no funding. The entire system was built and operated for profit - all the way down to the university lab level where you would think independent scientific research and education should take place. As you stated, major journals that are pumped out to front line professional providers, are filled with profit motivated biased studies that promote product A or method B. Then there is the brainwashing of the public mindset that reinforces the structure from the bottom up driven by big pharma though their media whores. The entire system has been designed and corrupted by special interests. Then there is the insurance industry that also drives part of that process to maximize profit at the expense of people's lives. Clinicians are forced into an even smaller box of acceptable extremely biased treatment modalities forced again by financial interests and not what is best for the patient. AI is adding a whole new dimension that is redefining medicine. Disease and its management are algorithmic results that have no need for the expertise of a human clinician. The results of that road may be a nightmarish page right out of a futuristic sci-fi novel. AI is an excellent tool when used as a tool. But when AI ends up in the driver's seat running the process and making the decisions, it will not end well for us as a species. Thank you for your response.
Thank you. Well said. Please post your thoughts on the clinical trials process. Often, trials are farmed out to “favorite” third parties to conduct. If the company, in this case Pfizer, is happy with the results then more clinical trials go their way. If they aren’t happy, it goes elsewhere next time. So in order to keep those multi million trials coming their way, those third parties know how to construct and engineer the trials to increase the odds for a favorable response.
Then the reports are written and submitted to the medical journals that are bloated with full page ads from these same drug companies. Without the ad revenue the journals cease to exist. So the editorial board considers which studies to include and which to reject. Is it any wonder that the only ones that see the light of day are those that find the drugs are well tolerated, show positive results, should be approved, etc?
The whole dam system is corrupt end to end IMHO. I’d love to read your thoughts.
Thank you. You seem to have a pretty good handle on how the whole process works and you hit the nails on their heads. I don't have much to add to what you so well summarized. Your conclusions are right on the money - pun intended.
The whole process was very frustrating and disheartening when I worked in research and later, clinical practice. What science should be researched for the good of humanity is sidelined for profit. If there is no pot of gold at the end of that rainbow there is no funding. The entire system was built and operated for profit - all the way down to the university lab level where you would think independent scientific research and education should take place. As you stated, major journals that are pumped out to front line professional providers, are filled with profit motivated biased studies that promote product A or method B. Then there is the brainwashing of the public mindset that reinforces the structure from the bottom up driven by big pharma though their media whores. The entire system has been designed and corrupted by special interests. Then there is the insurance industry that also drives part of that process to maximize profit at the expense of people's lives. Clinicians are forced into an even smaller box of acceptable extremely biased treatment modalities forced again by financial interests and not what is best for the patient. AI is adding a whole new dimension that is redefining medicine. Disease and its management are algorithmic results that have no need for the expertise of a human clinician. The results of that road may be a nightmarish page right out of a futuristic sci-fi novel. AI is an excellent tool when used as a tool. But when AI ends up in the driver's seat running the process and making the decisions, it will not end well for us as a species. Thank you for your response.