Guadeloupe is an archipelago and overseas department and region of France 
Guadalupe Island or Isla Guadalupe is a volcanic island located 241 kilometres (150 mi) off the west coast of Mexico 's Baja California Peninsula 
Our Lady of Guadalupe (Spanish: Nuestra Señora de Guadalupe), also known as the Virgin of Guadalupe (Spanish: Virgen de Guadalupe), is a Catholic title of the Blessed Virgin Mary associated with a series of five Marian apparitions in December 1531, and a venerated image on a cloak enshrined within the Basilica of Our Lady of Guadalupe in Mexico City. ...

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Makes me think of "Our Lady of Guadalupe." Mary is the crusher of demons. Perhaps Ole Joe remembered that he's supposed to be Catholic, but he's really not, he's a satanic pedo who knows that Mary don't like kid diddlers, so he knows he's in trouble. ;)

Are you speaking about Guadalupe the country? Or a name he mentioned?

Any Mexican would think first of Our Lady of Guadalupe, the patron saint of Mexico, often called just Guadalupe. But I can't believe Biden would know or respect that. Her feast day is Dec.12 and artistically she is represented as the Woman Clothed With the Sun as in Revelation.