He takes a seizure medication and is afraid to mix the two, plus he doesn't take a lot of meds because his stomach doesn't react well. Can he rub his paste on and it still be effective? Edit: Sorry I forgot to post he was diagnosed with "coof" last night.
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Consider DMSO - It seeps right into the body, carrying virtually anything it's mixed with. Will the horse paste + DMSO get it into his body? Definitely. Is it safe? Iouno and I wouldn't test it myself unless I were desperate.
The problem with dmso is just what you said. It takes everything into the body. You can ingest a lot of things that you wouldn't necessarily want reaching the blood stream though the skin. The digestive system is used to handling things the skin does not. You would be breaking the natural role of the skin keeping foreign material out.