Flu cases from 2012 to 2021πππ
(media.greatawakening.win)
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You sound reasonably knowledgeable regarding viruses, so I hope you can provide an answer to this question, "Since covid is considered a respiratory virus, what would happen to a healthy human if a very small amount of the covid virus (perhaps a half dozen virus "cells") was injected as a "skin pop" into them?" My thinking is that limiting the virus to a small area of the body with limited circulation would allow the person's immune system to easily attack it before it replicates to a dangerous level, unlike when introduced into the lungs. I hope to read your comments. Thank you.
There are very few viruses that can get past innate and cellular immunity and cause infection from βa half dozen virus βcellsβ.β
In general, I can only think of a few that are known to be that infectious.
Also, Iβm general, viruses do not want to kill their host. Usually the strains that mutate and survive are strains that remain highly infectious but not highly lethal.
Most complications from infection come from the bodyβs overactive response, things like βcytokine storm.β
I do antiviral drug discovery for a living. But drug discovery is largely tangential to all this.
As for your thinking, there's two things to note: The first is that the immunity that you're looking for is antibody production. But the second thing to note is that the primary way your body fights infection is without antibodies. Unfortunately antibodies require a ton of trial and error for the immune system so you're unlikely to develop any with only minor infection, particularly if it's quickly resolved.
Vaccines work by flooding the body with a shit ton of noninfectious analogs for the immune system to trial itself against, and absent that you won't confer immunity. Vaccines are hard to produce, impossible in many cases even. An HIV vaccine for example, has been a holy grail for decades.
So would a slow, ramping up, series of injections of diluted covid, with a new injection every few days, be a way for a human to eventually develop the antibodies?
The idea of continuous exposure. I don't know, maybe. Or at those dilute levels that aspect of the immune system would never get a chance. That's too far ourside my wheelhouse.