The answer according to the Bible is that this entire reality was originally created for God and the angels to use, with man being a created being to be a caretaker over this planet. There were never to be amputees, little kids dying of cancer or politicians killing their constituents.

This is all due to the 'sin', which is to say corruption that was created in this reality by Satan, and in turn humans. This entire reality will be one day destroyed along with everything in it, and a new reality will be given to those saved from this broken reality.

Just like many can't stand imperfection - God is a hyper-perfectionist, and we are told no one and nothing in this reality will be saved except through Jesus. The amputees, kids with cancer, etc are all evidence of a broken reality - and not due to any actions on God's part.

It is no different than you or I creating a Minecraft world that is corrupted by a hacker. No matter how good the Minecraft being's are, they would be forever corrupted due to the nature of their existence. God offers a way to pull your 'save file' out of this realm, and promises to insert it in the new reality.