I read somewhere many of the effects of cannabinoids and endocannabinoids are mediated by two G protein-coupled receptors (GPCRs), CB(1) and CB(2), although additional receptors may be involved. CB(1) receptors are present in very high levels in several brain regions and in lower amounts in a more widespread fashion. Without getting too deeply, there are medicinal properties of cannabinoids having low THC levels that are very beneficial to epileptics.
Of course all medicines should be used very sparingly and with vigilance. If you think of optimal balance, the human body always attempts to achieve this. It will continue to achieve optimal balance under the influence of a medicine or drug.
One example of this is steroid use. It is well known that anabolic steroids mimic testosterone and long term use causes reduced testosterone production. The condition can be permanent. Many body builders have found this out the hard way.
Another condition is called Post Finasteride Syndrome (PFS). Finasteride is marketed with the brand names Propecia and Proscar for treatment in men with male pattern hair loss and prostate issues. Use of finasteride works by decreasing the amount of the hormone dihydrotestosterone (DHT) in your body. DHT is a metabolite of testosterone. It has similar but much stronger effects. DHT is estimated to be three to six times more powerful than testosterone. Both hormones are classified as androgens.
Post Finasteride Syndrome (PFS) acts in many ways as steroids do and is often a permanent infliction in which causes reduced testosterone levels. Many individuals have to receive testosterone drugs for the rest of their lives.
The condition in the human body is always one of optimal balance. Alcoholics suffer from years of abuse whereby dopamine production becomes exhausted.
Cannabinoid Hypermesis Syndrome sounds like it may be a result of a similar infliction, in which optimal balance has been altered. The question is what has the Cannabinoid replaced in the body?
Alcoholics also have gaba system damage, which is the worst.
Not enough research on CHS yet to determine what is the exact situation. But the only cure is to quit, which seems like it fits because that is only way you can get rid of this horrendous shit.
I read somewhere many of the effects of cannabinoids and endocannabinoids are mediated by two G protein-coupled receptors (GPCRs), CB(1) and CB(2), although additional receptors may be involved. CB(1) receptors are present in very high levels in several brain regions and in lower amounts in a more widespread fashion. Without getting too deeply, there are medicinal properties of cannabinoids having low THC levels that are very beneficial to epileptics.
Of course all medicines should be used very sparingly and with vigilance. If you think of optimal balance, the human body always attempts to achieve this. It will continue to achieve optimal balance under the influence of a medicine or drug.
One example of this is steroid use. It is well known that anabolic steroids mimic testosterone and long term use causes reduced testosterone production. The condition can be permanent. Many body builders have found this out the hard way.
Another condition is called Post Finasteride Syndrome (PFS). Finasteride is marketed with the brand names Propecia and Proscar for treatment in men with male pattern hair loss and prostate issues. Use of finasteride works by decreasing the amount of the hormone dihydrotestosterone (DHT) in your body. DHT is a metabolite of testosterone. It has similar but much stronger effects. DHT is estimated to be three to six times more powerful than testosterone. Both hormones are classified as androgens.
Post Finasteride Syndrome (PFS) acts in many ways as steroids do and is often a permanent infliction in which causes reduced testosterone levels. Many individuals have to receive testosterone drugs for the rest of their lives.
The condition in the human body is always one of optimal balance. Alcoholics suffer from years of abuse whereby dopamine production becomes exhausted.
Cannabinoid Hypermesis Syndrome sounds like it may be a result of a similar infliction, in which optimal balance has been altered. The question is what has the Cannabinoid replaced in the body?
Alcoholics also have gaba system damage, which is the worst.
Not enough research on CHS yet to determine what is the exact situation. But the only cure is to quit, which seems like it fits because that is only way you can get rid of this horrendous shit.