This is true. Early treatment is critical to keeping the pathogen load down. It is the body's immune response to the pathogen that is individually variable and is the problem. This hypersensivity response can cause horrendous inflammation. Also, secondary bacterial infection can lead to pneumonia. Therefore, the earlier treatment is started, the more successful it will be at avoiding more serious complications. The 72 hour rule is applicable to any suspected acute viral respiratory infection and they usually run their course in 7 to 10 days. This is why using antivirals like Remdesivir in critical care settings long after the pathogen has left the crime scene is ridiculous and suspect. It flies in the face of normally accepted progression of acute respiratory viral infection.
Some people have digestive symptoms associated with this disease. Have some famotidine on hand as well. It is a H2 receptor antagonist while the diphenhydramine is first generation H1-antihistamine. Second generation H1-antihistamines include cetirizine (Zyrtec), loratadine (Claritin), and, fexofenadine (Allegra). These drugs do not cause drowsiness like the first generation drugs diphenhydramine and promethazine. A multidrug antihistamine approach with comitant steroid therapy has been used successfully by some clinicians to treat more serious cases of Covid. They recommend methylprednisone or prednisone versus dexamethasone which is what they use in the hospitals at doses too low to have any significant impact. Have some antibiotics on hand to treat possible secondary bacterial infection. This is why the azithromycin has been effective in some cases in combination with other drugs. You can get amoxicillin or some other antibiotics from online veterinary supply that sells fish antibiotics. They are the same drugs using the same dosages that are sold at the pharmacy. Stay well fren.
Thank you. Just trying to be useful. I am not a fan of long term use of antihistamines like diphenhydramine. There are some long term side effects and they can cause drowsiness. The drug has been associated with dementia and heart problems. Occasional use is fine, but I recommend the second generation H2 antagonists for occasional use. You are right about the quercetin inhibiting mast cell production and in divided doses throughout the day it can help. A low histamine diet in the midst of Rona would not be a bad idea for someone that already suffers from hypersensitivity and histamine dysregulation. Other supplements to consider are resveratrol, luteolin, and curcumin.
Cleaning house? Usually a person is too sick to go through the effort and I would suspect that it would be of limited value. Certainly air filtration is a must however. The hypersensitivity with Rona is internal triggering so that is where the focus needs to be. That said, the prevention of pathogen burden in the beginning is the best strategy to minimize the need for other intervention.
Thank you fren. I pray your aunt gets better. I was pretty sick myself about 5 months ago. Finally broke the fever on about day 5. I didn't get any of the respiratory stuff though. It was trying to get a foothold, but it never was able. I pounded the hell out of my supplements. I did have to start with some amox on day 7 because I seemed to be developing a secondary upper respiratory infection. The course of azithromycin did not seem to have an effect so I switched to amox. It did the trick.
I increased Vitamin D to 50K IU a day. When you are sick or challenged in anyway, Vit D levels can decrease by 50 percent in less than 24 hours. So, if a person is already deficient they will be knocked into the basement. Those that have levels of 30 to 40 ng/ml to begin with will have those levels decrease to 15 to 20 ng/dl. That is deficient. Low D is associated with poorer outcomes.
Do not give steroids until you are sure the acute infective stage is over. That would be about day 8. Usually what happens is a person starts to feel better and then on day 8 it turns - they cannot breath. That is the hypersensitivity cascade kicking in. That is when combination antihistamine and steroid therapy is probably indicated. If you think the respiratory symptoms are getting worse, antibiotics may help. But, it sounds like your aunt is got a good chance here. She is lucky to have you. See if you have a provider in your area that can administer IV supplemental therapies if you think she needs a good boost. There is all kinds of things they can administer to help her immune system - as long as it is not specifically for the Rona. ; )
This is true. Early treatment is critical to keeping the pathogen load down. It is the body's immune response to the pathogen that is individually variable and is the problem. This hypersensivity response can cause horrendous inflammation. Also, secondary bacterial infection can lead to pneumonia. Therefore, the earlier treatment is started, the more successful it will be at avoiding more serious complications. The 72 hour rule is applicable to any suspected acute viral respiratory infection and they usually run their course in 7 to 10 days. This is why using antivirals like Remdesivir in critical care settings long after the pathogen has left the crime scene is ridiculous and suspect. It flies in the face of normally accepted progression of acute respiratory viral infection.
Some people have digestive symptoms associated with this disease. Have some famotidine on hand as well. It is a H2 receptor antagonist while the diphenhydramine is first generation H1-antihistamine. Second generation H1-antihistamines include cetirizine (Zyrtec), loratadine (Claritin), and, fexofenadine (Allegra). These drugs do not cause drowsiness like the first generation drugs diphenhydramine and promethazine. A multidrug antihistamine approach with comitant steroid therapy has been used successfully by some clinicians to treat more serious cases of Covid. They recommend methylprednisone or prednisone versus dexamethasone which is what they use in the hospitals at doses too low to have any significant impact. Have some antibiotics on hand to treat possible secondary bacterial infection. This is why the azithromycin has been effective in some cases in combination with other drugs. You can get amoxicillin or some other antibiotics from online veterinary supply that sells fish antibiotics. They are the same drugs using the same dosages that are sold at the pharmacy. Stay well fren.
Thank you. Just trying to be useful. I am not a fan of long term use of antihistamines like diphenhydramine. There are some long term side effects and they can cause drowsiness. The drug has been associated with dementia and heart problems. Occasional use is fine, but I recommend the second generation H2 antagonists for occasional use. You are right about the quercetin inhibiting mast cell production and in divided doses throughout the day it can help. A low histamine diet in the midst of Rona would not be a bad idea for someone that already suffers from hypersensitivity and histamine dysregulation. Other supplements to consider are resveratrol, luteolin, and curcumin.
Cleaning house? Usually a person is too sick to go through the effort and I would suspect that it would be of limited value. Certainly air filtration is a must however. The hypersensitivity with Rona is internal triggering so that is where the focus needs to be. That said, the prevention of pathogen burden in the beginning is the best strategy to minimize the need for other intervention.
Thank you fren. I pray your aunt gets better. I was pretty sick myself about 5 months ago. Finally broke the fever on about day 5. I didn't get any of the respiratory stuff though. It was trying to get a foothold, but it never was able. I pounded the hell out of my supplements. I did have to start with some amox on day 7 because I seemed to be developing a secondary upper respiratory infection. The course of azithromycin did not seem to have an effect so I switched to amox. It did the trick.
I increased Vitamin D to 50K IU a day. When you are sick or challenged in anyway, Vit D levels can decrease by 50 percent in less than 24 hours. So, if a person is already deficient they will be knocked into the basement. Those that have levels of 30 to 40 ng/ml to begin with will have those levels decrease to 15 to 20 ng/dl. That is deficient. Low D is associated with poorer outcomes.
Do not give steroids until you are sure the acute infective stage is over. That would be about day 8. Usually what happens is a person starts to feel better and then on day 8 it turns - they cannot breath. That is the hypersensitivity cascade kicking in. That is when combination antihistamine and steroid therapy is probably indicated. If you think the respiratory symptoms are getting worse, antibiotics may help. But, it sounds like your aunt is got a good chance here. She is lucky to have you. See if you have a provider in your area that can administer IV supplemental therapies if you think she needs a good boost. There is all kinds of things they can administer to help her immune system - as long as it is not specifically for the Rona. ; )
God bless fren.