I don't know what you're taking now, but my SiL had arthritis bad enough that she almost had to go on disability (tough to do office work when your hands don't function well). This was thirty-some years ago.

Her doc told her to decide what position she wanted her hands and fingers to be in because eventually they'd more or less freeze in place. The drugs they were pushing at the time were VERY bad for the liver; I don't know what they're prescribing now.

She decided to use SAMe, 800mg, daily. Nothing else. Her hands were soon fine and have remained so to the present day. SAMe, as it happens, is also very protective of the liver and in larger doses (1200mg or more) shows about the same positive results against depression as prescription drugs.

She could probably have achieved the same result with glucosamine and chondroitin; many people have had good results with that. Glucosamine also extends the lifespan of nematodes and mice -- "longer life" is actually becoming a not-uncommon side effect of a growing list of supplements. A recent HUMAN study found a dramatic reduction of mortality from any cause in a 107-month long study of over 16,000 participants.