The objective of this study was to investigate the biodistribution of luciferase expressed
by the LNP-formulated modRNA using bioluminescence measurements in BALB/c
mice, as well as innate immune system activation, formation of antibodies against
luciferase and T-cell activation.
Basically they were using mRNA to encode luciferase so that the body creates it, and testing its effects.
Basically they were using mRNA to encode luciferase so that the body creates it, and testing its effects.