Most importantly is that the physical wiring in the brain is completely different between a biological male and female. This wiring in the brain starts to differ in the womb. Sexual dimorphism is most often attributed in terms of physical attributes. These biological sex differences arise not only from epigenetic hormone actions during developmental sensitive periods but also from an individual’s experiences interacting with the outside world. And that results in human brains that show visible differences in terms of size, appearance, and function between the sexes of a species. The same principles applies to humans. A cartoonish analogy would be likening testosterone hormone treatment in a woman to that of a mortal human attempting to hold the Infinity stone in the Marvel movie 'End Game'. Women do not have the wiring already existing in males. It is a molotov cocktail that will destroy the individual. This should never be done.