I just watched a video that suggested Thiamine (B1) and agmatine for neuropathy and fibro.

Here's what ChatGPT (Bing) offered:

Agmatine is a naturally occurring compound that is derived from the amino acid L-arginine. It was first discovered in 1910, and since then, it has been studied for its potential therapeutic effects.

Agmatine is primarily found in the brain, where it acts as a neuromodulator and neurotransmitter. It is involved in regulating a variety of processes in the central nervous system, including neurotransmission, neuroprotection, and the formation of new neurons.

Research on agmatine suggests that it may have several potential health benefits. Some studies have shown that agmatine has analgesic (pain-relieving) properties and may be helpful in managing chronic pain conditions. It has also been investigated for its potential antidepressant and anxiolytic (anti-anxiety) effects.

Agmatine has been found to have vasodilatory effects, meaning it can widen blood vessels and improve blood flow. This property has led to research exploring its potential in managing cardiovascular conditions such as hypertension (high blood pressure).

Additionally, agmatine has been studied for its potential role in managing neurodegenerative diseases such as Alzheimer's and Parkinson's. It has been shown to have antioxidant and neuroprotective properties, which may help protect against neuronal damage.

It's important to note that while there is promising research on agmatine, more studies are needed to fully understand its mechanisms of action and its potential therapeutic applications. As with any supplement or medication, it is advisable to consult with a healthcare professional before using agmatine, especially if you have any underlying medical conditions or are taking other medications.