The key part of your response is "over time." When someone is dealing with arterial calcification, that itself has taken place over a long period of time, and which needs to be addressed in a more timely manner to lower risk, then IV chelation therapy is by far the best choice. If you have some research on the results of K2 therapy reducing arterial calcifications I would be interested in looking at it. I have not seen any that shows any substantial reductions in arterial decalcifications in the literature other than theoretical assumptions; however, I do not disregard the assumptions because they are based on good biochemistry theory. But until that theory can be demonstrated in clinical results, they remain just that - good theory. Taking K2 certainly is not going to harm most people. So if one can start early enough and keep up with a regiment, then good. But that is where most people fall down. It is difficult to keep up a nutritional supplementation regiment over the long term. Thank you for your comment.