New study: Blood distribution of SARS-CoV-2 lipid nanoparticle mRNA vaccine in humans

👉🏻 https://www.medrxiv.org/content/10.1101/2024.07.25.24311039v1

• "Taken together, our results suggest vaccine mRNA lipid nanoparticles recirculate for up to 1 month post-vaccination." (!)
• "... mRNA lipid nanoparticles remain intact and travel from injection sites or lymph nodes into blood stream within 4 hours post-vaccination."
• "The rapid dissemination of mRNA lipid nanoparticles in blood found in our study is consistent with the recent findings on the detection of mRNA in breast milk at 3–45 hours post-vaccination."
• "The proteins and lipids bind to mRNA lipid nanoparticles in either lymph or plasma, forming so called “biomolecular corona", which could influence uptake and immunogenicity of the vaccines."

Varicella zoster reactivation after COVID-19 vaccination

👉🏻 https://www.cell.com/heliyon/fulltext/S2405-8440(24)08279-3?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2405844024082793%3Fshowall%3Dtrue

"This case highlights the importance of considering varicella zoster reactivation in a patient presenting with encephalitis or pneumonia post SARS-CoV-2 vaccination, especially considering the mortality and morbidity associated with these manifestations, if not promptly treated."

Atypical hemolytic-uremic syndrome after COVID-19 vaccination

👉🏻 https://onlinelibrary.wiley.com/doi/10.1002/iid3.1270

• "... it is vital to acknowledge the emerging adverse events associated with these vaccines."
• "We agree on the need for more reports of clinical trials are needed to increase understanding of the clinical characteristics and mechanism of the physiopathology of TMA associated with COVID-19 vaccination."