From the link:

A major new review paper titled, High-dose vitamin C: A promising anti-tumor agent, insight from mechanisms, clinical research, and challenges, analyzed 150+ studies and found that when vitamin C reaches true pharmacologic levels (20–30 mM), it behaves like a targeted, tumor-selective therapy — something past trials missed by under-dosing. The evidence base spans decades of laboratory, animal, and early-phase clinical research.

The authors outline four major anti-cancer mechanisms of high-dose vitamin C — pro-oxidative tumor cytotoxicity, epigenetic reprogramming, suppression of oncogenic signaling pathways, and powerful immune activation.

From me:

In the mid-1940s, a prominent American doctor published an article in a popular magazine, perhaps Saturday Evening Post (I read the article in the 1970s -- in a doctors office! -- and don't remember the names of the doctor or the mag).

The article discussed his clinic's success at CURING POLIO with intravenous vitamin C, using infusions of (as I recall) 20 grams (20,000 mg) daily. Ten years later, people were STILL dying of polio, and doctors were completely ignoring vitamin C therapy for it.

I was unable to find that article with a web search, then or now. But I DID find other proof of both the efficacy of vitamin C in curing polio and other viral infections, AND of the cover-up, which (as often with vitamin C "research") involved doing studies with FAR lower dosages than the ones used in SUCCESSFUL work, and then basically saying "See, it doesn't work."

See this search page, with links and the Brave AI summary shown below:

In the 1940s, research into vitamin C as a treatment for polio was conducted, notably by Dr. Claus W. Jungeblut. His 1939 study demonstrated that synthetic ascorbic acid could inactivate poliomyelitis virus in vitro, rendering it non-infectious when tested in rhesus monkeys.

Jungeblut also reported that administering vitamin C to monkeys infected with the virus led to a reduction in disease severity and enhanced resistance, suggesting a potential therapeutic effect.

However, subsequent attempts by Dr. Albert Sabin to replicate these results failed, and his negative findings were influential in halting further research into vitamin C therapy for polio at the time.

Later, in 1949, Dr. Frederick R. Klenner published a report detailing his clinical use of high-dose intravenous vitamin C in treating polio patients. He claimed to have successfully treated 60 polio patients, all of whom recovered fully without paralysis, including those with advanced disease who would typically require an iron lung.

Klenner's treatment regimen involved massive doses of vitamin C—up to 20,000 mg daily—administered intravenously or intramuscularly, often following initial oral megadoses. He attributed the success of his treatment to the high and sustained blood levels of vitamin C, which he believed created an unfavorable environment for viral replication.

Despite these reports, the medical community largely ignored the findings, and vitamin C therapy was not adopted as a standard treatment for polio, especially as the development of the Salk and Sabin vaccines progressed. The potential of vitamin C as an antiviral agent was thus effectively sidelined for decades, though some researchers have since argued that the early results were overlooked due to inadequate dosing in follow-up studies.

Give Linus Pauling his due. He was the pioneer in Vitamin C research.

Is there a chart with the dosage / weight

An associate at one of the big hospitals in Baltimore (main campus; Oncology) told me maybe a year ago they were dosing a patient with 100 grams of vitamin C. I kind of dismissed it momentarily until I understood they were talking about grams and not milligrams.

Dosing was by IV and there were other drugs administered simultaneously to prevent the patient’s heart from shutting down.

I asked for a follow up but they had not tracked that particular case further.

I guess the point is the big hospital oncology treatments have included vitamin C as one of the treatment medicines routinely (albeit at much lower doses) and are now at least experimenting with high dose vitamin C.

I know a woman whose husband was hospitalized during CV - late 30s/early 40s. This was the first wave, and he got pretty sick. She was actually prepping her kids for the fact that he might not make it. But she was relentless (she has a talent for pushing to get what she wants but isn't an asshole about it. Just patient and persistent.) Anyway, she was reading everything she could and advocated to try high dose Vitamin C via IV, which allowed him to finally turn the corner.

Ascorbic acid supplements are poison.

You need vitamin C, but injecting it into your body to cure cancer is bullshit. My dad tried this shit, and died. Think what you want. You've been warned.