You said that the J and J vaccine was an attenuated live vaccine, ie. more like a conventional vaccine.
AFAIK, this isn't right. The J and J works similarly to the mRNA "vaccines" to make the body produce spike proteins. The difference is that it uses an adenovirus to inject engineered DNA into the cell instead. Not attenuated adenovirus DNA, but DNA instructions for the spike proteins. The end result is similar to the other vaccines, the body is made to create spike proteins in our own cells.
I'm just not sure that it's weaker. It's different from a live attenuated virus which trains the immune system but can't reproduce.
The adenovirus vector is a trojan horse for the DNA injection, which can reproduce ( can continually produce spike proteins ) it's not different in end result to the mRNA "vaccines" because they introduce mRNA which the cells uses to continually make spike proteins. Both technologies cause the cells to continually make spike proteins.
Thanks for your insights. Maybe edit or add the additional information to your original post to keep it updated. It's useful to keep the best info in one place. Easy to overlook important info that only appears in the comments.
This is a fantastic post. Thank you very much!
I have a technical disagreement though.
You said that the J and J vaccine was an attenuated live vaccine, ie. more like a conventional vaccine.
AFAIK, this isn't right. The J and J works similarly to the mRNA "vaccines" to make the body produce spike proteins. The difference is that it uses an adenovirus to inject engineered DNA into the cell instead. Not attenuated adenovirus DNA, but DNA instructions for the spike proteins. The end result is similar to the other vaccines, the body is made to create spike proteins in our own cells.
Here is an explanation from the NYTimes
https://www.nytimes.com/interactive/2020/health/johnson-johnson-covid-19-vaccine.html
No problem.
I'm just not sure that it's weaker. It's different from a live attenuated virus which trains the immune system but can't reproduce.
The adenovirus vector is a trojan horse for the DNA injection, which can reproduce ( can continually produce spike proteins ) it's not different in end result to the mRNA "vaccines" because they introduce mRNA which the cells uses to continually make spike proteins. Both technologies cause the cells to continually make spike proteins.
Thanks for your insights. Maybe edit or add the additional information to your original post to keep it updated. It's useful to keep the best info in one place. Easy to overlook important info that only appears in the comments.
My understanding too.