If you want another example proving the hygiene hypothesis, take a look at faustmanlab.org. Dr Faustman, funded without big pharma (crowdfunded, more or less), essentially proved that type 1 diabetes is caused by lack of exposure to mycobacteria tuberculosis. There are lots of others, mostly circumstantial, but you may know of them already.
You can find it on that website under the publications tab. It came out in both the journal of internal medicine, and the Lancet in March and April of last year. Would've been big news in medical journalism, but, ya know, something bigger usurped the limelight. As far as scientific articles are concerned, it's amazingly brief and to the point, only 4-5 pages and easy to read, iirc. The TB vaccines provide a similar function to the actual bacteria, but do so less effectively, leaving a portion of people more prone to develop type 1 diabetes than they would have with either the real bacteria (or a stronger more effective vaccine).
If you want another example proving the hygiene hypothesis, take a look at faustmanlab.org. Dr Faustman, funded without big pharma (crowdfunded, more or less), essentially proved that type 1 diabetes is caused by lack of exposure to mycobacteria tuberculosis. There are lots of others, mostly circumstantial, but you may know of them already.
First I'd heard of that, that'd be pretty wild.
You can find it on that website under the publications tab. It came out in both the journal of internal medicine, and the Lancet in March and April of last year. Would've been big news in medical journalism, but, ya know, something bigger usurped the limelight. As far as scientific articles are concerned, it's amazingly brief and to the point, only 4-5 pages and easy to read, iirc. The TB vaccines provide a similar function to the actual bacteria, but do so less effectively, leaving a portion of people more prone to develop type 1 diabetes than they would have with either the real bacteria (or a stronger more effective vaccine).