No? This is just blatantly false. Industrial alcohol continued to be produced during prohibition. Most pharmaceuticals, chemicals, etc. used and STILL use some form of industrial alcohol in their formulation. IN FACT before the birth of the modern pharmaceutical industry, like 90% of "pharmaceuticals" came in the form of some kind of alcoholic tonic that was basically ethanol mixed with various herbs and spices with medicinal properties.

The main push for temperance was women, like OVERWHELMINGLY women. Besides, even if we produced ZERO food from our wheat and corn supplies and converted ALL OF IT into ethanol it would NEVER meet our energy needs. Much less even back then. Much less the energy needs of the entire world.

The main reason we went to oil based fuels is because its THE MOST energy dense fuel on the planet. Only nuclear stuff is more energy dense and that's not exactly practical for cars, trucks, trains, etc.

MOST vehicles before prohibition were dual fuel (meaning they could run off gasoline OR ethanol) because at the time many places were remote with no access to gasoline yet but you COULD make your own moonshine and throw it in the tank if you wanted to, which made cars and trucks more feasible and allowed for greater adoption. By the time prohibition was over, the gasoline infrastructure had spread enough that it no longer made sense to engineer dual fuel vehicles for the mass market so they simply stopped until demand started spiking again in the 80s and 90s and we got "mixed fuel" vehicles that are designed to run on a set ratio mix of gasoline to ethanol.