Superparamagnetic nanoparticle delivery of DNA vaccine (SPIONS)
(pubmed.ncbi.nlm.nih.gov)
?️ DISCUSSION ?
Comments (18)
sorted by:
Abstract The efficiency of delivery of DNA vaccines is often relatively low compared to protein vaccines. The use of superparamagnetic iron oxide nanoparticles (SPIONs) to deliver genes via magnetofection shows promise in improving the efficiency of gene delivery both in vitro and in vivo. In particular, the duration for gene transfection especially for in vitro application can be significantly reduced by magnetofection compared to the time required to achieve high gene transfection with standard protocols. SPIONs that have been rendered stable in physiological conditions can be used as both therapeutic and diagnostic agents due to their unique magnetic characteristics. Valuable features of iron oxide nanoparticles in bioapplications include a tight control over their size distribution,
magnetic properties of these particles, and the ability to carry particular biomolecules to specific targets. The internalization and half-life of the particles within the body depend upon the method of synthesis. Numerous synthesis methods have been used to produce magnetic nanoparticles for bioapplications with different sizes and surface charges. The most common method for synthesizing nanometer-sized magnetite Fe3O4 particles in solution is by chemical coprecipitation of iron salts. The coprecipitation method is an effective technique for preparing a stable aqueous dispersions of iron oxide nanoparticles. We describe the production of Fe3O4-based SPIONs with high magnetization values (70 emu/g) under 15 kOe of the applied magnetic field at room temperature, with 0.01 emu/g remanence via a coprecipitation method in the presence of trisodium citrate as a stabilizer.
Naked SPIONs often lack sufficient stability, hydrophilicity, and the capacity to be functionalized. In order to overcome these limitations, polycationic polymer was anchored on the surface of freshly prepared SPIONs by a direct electrostatic attraction between the negatively charged SPIONs (due to the presence of carboxylic groups) and the positively charged polymer. Polyethylenimine was chosen to modify the surface of SPIONs to assist the delivery of plasmid DNA into mammalian cells due to the polymer's extensive buffering capacity through the "proton sponge" effect.
Also more info at: https://www.sciencedirect.com/topics/medicine-and-dentistry/superparamagnetic-iron-oxide-nanoparticle
Looking at this paper, I don't think these particular magnetite nanoparticles (or any similar small crystal) would be compatible with the Ad26 (J&J/AZ) vaccines, nor the mRNA (P/M) vaccines (at least not as presented in this paper).
These magnetite nanoparticles, due to a slight negative charge on their surface, as well as compatible hydrophobicity attract positively charged slightly hydrophobic polymers (a lot of amine groups and carbon chains) as a sort of coat. This polymeric coating then attracts the negatively charged backbone of the genetic material to be transfected (RNA/DNA). The magnetic nature is then exploited for transfection.
Neither the lipid nanoparticles (mRNA vaccines) nor the adenovirus vaccines have these types of positively charged polymers as listed ingredients, nor would they, as they are self contained with the genetic material inside and employ different methods of transfection. I am not seeing (at least from this paper) how these types of systems would aid directly in delivery of these technologies; unless they aren't what they say they are (like at all).
I'm still trying to rectify the anecdotal evidence of the magnetic effect of the vaccines though. This is a good find, and may lead to an understanding of what is going on, even if not directly (assuming those anecdotes are true).
Bingo. Now we have the reason why magnets are sticking to the COVID jab sites.
Jim Stone points out that MRI scans will be deadly to anyone who has taken the vax that includes nano-particles.
Good find. The Aussies published this in 2014.
Nice find pede... possible explanation for why magnets are sticking to people where they got the death jab
Supercalifragilisticexpialidocious nanoparticles? Holy Mary Poppins, Batman!
Great minds think alike. I was about to post something similar. :)
An open access version of the whole paper is here.
I am not sure if this is a technology that is applicable to the current vaccines. I am looking into it more. From what I've read so far, it's designed to aid in transfection for other types of transfection technologies, not the lipid nanoparticles nor the adenoviruses (other polymers that are used to surround genetic material to be delivered into a cell). I'm not sure though, still looking.
Thank you
Good find! Thank you.
This explains the video I saw today of people sticking a magnet to the location on their arm where they got the jab.
https://odysee.com/@Mukunda-dasa108:1/Magnet-Medley---Compliation-of-Magnets-Sticking-the-Convid-1984-Injection-Sites...:b
Is it possible that the nanoparticles are not included for their interaction with the vaccine itself, but the vaccine is the cloak behind the delivery of the magnetic particles?
The entire purpose would be to load up the crowd with resonant receptors,
What might the resonant frequency of these particles be ?
could they be excited/activated by different frequencies via RF ?
different frequencies for different effects inside the human carrier ?
A type of mass control technique ? crowd behavioural control?
Via 5g transmitters.
Just me speculating on possibilities,
The whole “human 5G antenna” is the conclusion I keep coming to. We’ve heard about the dangers of 5G years before the PLANdemic. Not only are there videos of magnets sticking to the injection site, but there are also reports of the injected person having an elevated EMF reading. Flip on the 5G and who knows what they might be able to do to these people.
Possible explanation for why magnets are sticking to people's arms where they got the death jab
What?
Magnets sticking to site of death jab