A prion is an abnormally folded protein. It would either have to enter because your skin cells let it in (not gonna happen), it survived your nasal cavities, your saliva, your stomach acid, and your immune system. Any of which will denature a protein. Once a protein has lost its folds it is useless and can't spontaneously get them back.
Proteins are chains of amino acids, but their entire functions relies on how they fold. That is why drugs can only imitate them, but can never be them. Cocaine is an imitation of dopamine, but since it's not actual human dopamine it often gets stuck on the dopamine receptor and doesn't come off. This is what causes the damage from cocaine use. (like a key that opens the door but gets permanently wedged in the lock). Real human dopamine wouldn't do that.
You are not going to get prions from another human unless you eat that person. I.e. cannibalism. If they have kuru in their brain and you eat their brains you could be at risk to get kuru from the massive intake of their contaminated brain tissue.
There is zero chance you'll get it from their sweat, urine, fece, saliva, ect. Those all denature proteins. But if you eat that person, especially their brains, then yes, you are at risk to get a prion disease like kuru.
Even significant exposure to prions often requires 10+ years to incubate into actual symptoms. A singular prion may take over an average human lifetime to fully incubate.
Yes, and I also imagine the body would recycle the prions early on.
This would be normal housekeeping in a fit person if there weren't too many prions.
What I understand, the brain cells don't commit apoptosis and regenerate, so the spike proteins wouldn't be developing there, correct? There's somewhere else in the body that doesn't go thru this as well - I just can't find it right now.
Spez: Nerve cells and Cardiovascular cells don't go through apoptosis along with brain cells.
It only takes a single abnormal prion to cause "mad cow disease".
The mechanism of BSE transmission is not well understood. Even if this is true (which is not certain) it would take many years for such an infection to reach the stage of showing disease effects.
You reveller!
A prion is an abnormally folded protein. It would either have to enter because your skin cells let it in (not gonna happen), it survived your nasal cavities, your saliva, your stomach acid, and your immune system. Any of which will denature a protein. Once a protein has lost its folds it is useless and can't spontaneously get them back.
Proteins are chains of amino acids, but their entire functions relies on how they fold. That is why drugs can only imitate them, but can never be them. Cocaine is an imitation of dopamine, but since it's not actual human dopamine it often gets stuck on the dopamine receptor and doesn't come off. This is what causes the damage from cocaine use. (like a key that opens the door but gets permanently wedged in the lock). Real human dopamine wouldn't do that.
You are not going to get prions from another human unless you eat that person. I.e. cannibalism. If they have kuru in their brain and you eat their brains you could be at risk to get kuru from the massive intake of their contaminated brain tissue.
There is zero chance you'll get it from their sweat, urine, fece, saliva, ect. Those all denature proteins. But if you eat that person, especially their brains, then yes, you are at risk to get a prion disease like kuru.
So don't eat people.
We'll just call that universally sound advice, no matter the topic of conversation.
Even significant exposure to prions often requires 10+ years to incubate into actual symptoms. A singular prion may take over an average human lifetime to fully incubate.
Yes, and I also imagine the body would recycle the prions early on. This would be normal housekeeping in a fit person if there weren't too many prions.
Yes, I did think of that.
I reckon it doesn't. I think that it might take lots of prions before your brain can't just clear it up.
By the way, look at this article.
https://naturalsociety.com/new-study-coconut-oil-helps-remove-amyloid-plaques-brains-alzheimers-patients/
What I understand, the brain cells don't commit apoptosis and regenerate, so the spike proteins wouldn't be developing there, correct? There's somewhere else in the body that doesn't go thru this as well - I just can't find it right now.
Spez: Nerve cells and Cardiovascular cells don't go through apoptosis along with brain cells.
The mechanism of BSE transmission is not well understood. Even if this is true (which is not certain) it would take many years for such an infection to reach the stage of showing disease effects.
It may be understood and purposely obscured. http://www.madcow.pamrotella.com/
I don’t know, but it makes a lot of sense to me.
Oh interesting! Thank you very much!
I found this very interesting article on mad cow:
http://www.madcow.pamrotella.com/
I think he’s on the right track. If so, there are certain conditions that must be met before mad cow can occur.
I always thought it was suspicious how many cows they found with the disease, yet we didn’t see very many (relatively) in humans.
The bad news means that if he’s right, they know exactly how to cause mad cow and can easily do it.