I have had migraine (with vertigo, but they don’t always happen at same time) for over 15 yrs, and been recently diagnosed with Meniere’s.
My neurologist prescribed Ajovy injection for me about a year ago, I stopped taking it after a few months because the price skyrocketed from $5 to over $700. That’s when all the stuff about what’s in the vaxx started coming out. About a month ago I went back for my follow appointment and told him about the price change. So he was able to prescribe it for me for $5 again at the pharmacy. It’s a once a month injection. But now because of what’s in the vaxx, I’m worried about the contents of this medicine, so still have not taken it.
Does anyone have any thoughts about this medicine?
Here is the some info on Ajovy ... Fremanezumab-VFRM ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422958/
~~Some info from this site ...
Fremanezumab-vfrm (hereafter referred to as fremanezumab) [AJOVY™] is a fully humanized monoclonal antibody (IgG2Δa) developed by Teva Pharmaceuticals to selectively target calcitonin gene-related peptide (a vasodilatory neuropeptide involved in the pathophysiology of migraine). Its use has been associated with significant reductions in migraine frequency, the requirement for acute headache medication use and headache-related disability compared with placebo in multinational, phase III studies, and in September 2018 fremanezumab was approved by the US FDA for the preventive treatment of migraine in adults. A regulatory assessment for fremanezumab as a preventive treatment of migraine in adults is underway in the EU. Fremanezumab is also undergoing phase III development for the preventive treatment of cluster headache (although a phase III chronic cluster headache study has been suspended due to the results of a prespecified futility analysis) and phase II development for the preventive treatment of post-traumatic headache disorder. This article summarizes the milestones in the development of fremanezumab leading to this first approval in the USA for the preventive treatment of migraine in adults.
~~It looks like it originally came from Pfizer ...
In January 2013, Labrys Biologics acquired the worldwide rights to fremanezumab from Pfizer [8]. Under the terms of the agreement, Pfizer will be eligible to receive milestone payments and sales royalties [8]. In July 2014, Teva Pharmaceutical Industries (hereafter referred to as Teva) acquired Labrys Biologics (and the fremanezumab programme) for an upfront payment of US$200 million and contingent payments of up to US$625 million (subject to the achievement of certain development milestones) [9, 10]. In May 2017, Teva and Otsuka Pharmaceuticals (hereafter referred to as Otsuka) entered into a development and commercialization agreement [11]. Under the terms of this agreement, Otsuka acquires exclusive rights to fremanezumab and will fund clinical studies in Japan, while Teva receives a payment of US$50 million and will be eligible for milestone payments upon filing and regulatory approval in Japan and upon the achievement of revenue targets [11].
Teva is the company that has Ajovy now ...
https://www.tevapharm.com/search-results/?keywords=Fremanezumab
Yeah... I'm a Type 1 Diabetic who will die without expensive injections of insulin before every meal, thanks to a horrific reaction to Chicken Pox vaccine when I was three years old.
I appreciate your concern because I'm worried too, but I don't have a choice.
I wonder if they will eventually attempt to deny filling insulin scripts to unvaxxed pure-bloods like myself.
I'm not enjoying this show.
http://www.oxygenhealingtherapies.com/Ozone_and_Diabetes.html
https://pubmed.ncbi.nlm.nih.gov/12532590/
I think I can offer you some good, solid information and recommendations.
I have been a chronic migraine sufferer now, for about twelve years. It started from a long-term exposure to formaldehyde fumes coming from a sofa, of all things. I had it tested, sounds crazy. Long story.
Anyway, I use all kinds of triptans to help manage it, having to rotate through them because of a tolerance problem. With me, I also have an immune inflammatory response inside my skull, so when necessary, I also use low-dose doxepin as a heavy-duty antihistamine to knock the immune component back. I have also been taking Aimovig since it came out, using their $5 co-pay program. Since covid, I am becoming more and more concerned that the injection could become spiked, although Novartis and Amgen aren't involved with the vaccines.
But here's the thing. You mentioned Meniere's. Are you aware of the connection between celiac/gluten sensitivity and migraines, a whole host of other neurological symptoms, as well as Meniere's? https://www.glutenfreesociety.org/gluten-sensitivity-and-vertigomenieres-disease/ I have recently discovered I have adult-onset celiac, probably brought on by the formaldehyde exposure. Celiac doesn't necessarily manifest in gastro symptoms: https://pubmed.ncbi.nlm.nih.gov/15608953/ There are a lot of links if you search using these keywords.
What you need to do is have your doctor write you labs for celiac DNA, as well as gliadin antibodies. You can only have the antibody test, as well as the biopsy, performed while you are consuming gluten. Otherwise, if you go gluten-free, these tests will come up negative even though you might be positive. The difference between celiac gastro and celiac neuro is the recovery time. Gastro patients can start noticing improvement within six weeks or so of going gluten-free. Neuro patients may require two years.
This is just a summary of what you should know. I can provide more information if you like. Best wishes.
Thank you! I am reading on it now. I will call my doctor next week and ask about it. Can’t believe neither my neurologist or ENT never considered this? I go to my neurologist for migraines & ENT for Meniere’s. Just found out that my ENT retired without offering his patients options for a new doctor. So now I have to find a new ENT to treat my Meniere’s.
I have the same issue that comes and goes. I simply take sumatriptan -generic and knocks it out. I take Benadryl when the dizziness is too bad with the fluid in my ears. About $7 per script. Ive taken this for years only as needed and I’m very skeptical of trying new products they bring to market. Just my 2 cents.
Yes I have sumatriptan also that I take, and can take it even if I take the injection. This medicine is supposed to help to not have so many headaches, which would mean less times I would have to take sumatriptan. But since all the information has come to light about what’s in the vaxx and Pfizer (along with the other pharma companies), I’m concerned about injecting myself with anything, you know?
sorry, not familiar with the medication, but I know the doctors really don't care what they give you, they just like to prescribe. I had a stroke/my medications for a month in hospital was 30,000. left there with 14 pills a day, I'm now down to 1.
used to have a lot of headaches too, now I don't; my blood pressure is lower & I don't work anymore. Do you check your BP? have you tried magnesium? getting your blood checked for deficiencies? my electrolytes were a mess, was low on potassium, etc. felt so much better once everything was balanced. a better diet, less caffiene/alcohol helps a lot, I refuse a lot of things because I don't want a headache:(
I cannot help you with the medicine. However, I'm also a migraine sufferer. Mine are linked to hormones, and I used to get 1-2 a month. My doctor didn't want to prescribe any hardcore migraine medicines because she said people build up a tolerance, and it can make migraines worse over time to where the person has to get stronger and stronger medicines. I've seen this happen with my mom. My doctor has me take 2 small doses of magnesium oxide a day, 12 hours apart. And if I get a breakthrough migraine, I take Dramamine. She also said Benadryl would work instead of Dramamine, but it seems to linger and make me too drowsy.
I personally have had so many weird reactions to various pharmaceutical products that I prefer tried and true old school medicines, and hate trying newer medicines that haven't been around long. Once the older medicines are out of patent and can become generic, pharmaceutical companies are no longer making money off of them. So they invent new shit with more side effects that requires more drugs to fight the side effects. No thanks!
Migraines are no fun, and vertigo isn’t either, especially the Meniere’s vertigo. Lord I don’t wish that on anyone. It is worse than regular vertigo. To me there is a difference, I don’t I know if anyone else thinks the same way, but being I have both I feel a big difference. That’s how I knew something else was wrong with me. It took me like a year to finally get diagnosed, and not just any doctor can diagnose and treat you for Meniere’s apparently.
They definitely are not. People who don't get them don't understand, either.
I've been asked if I have Meniere's, but never diagnosed. I have hearing loss, but it's nerve damage from when I was a kid. I don't have very good balance and get dizzy when moving around. When I get a bad migraine and the room starts spinning and I'm nauseous, that's when the Dramamine helps a lot. So, I'm not sure if it would help with Meniere's vertigo.
I had a female neurologist once tell me she wouldn’t recommend Aimovig despite my migraines being so bad I couldn’t function because they didn’t know the long term effects.
When it comes to medications and medical advice, you always maintain the right to a second opinion. Or a third.
It seems the fully human monoclonals have less side effects than some of the mouse/other antibodies used that caused problems for MS patients and arthritis patients that took them. I’m not a doctor, but that’s at least what I was told when I had questions about sotrovimab and COVID.
As a fellow migraine sufferer, I’d recommend you see if you can find a doctor or acupuncturist in your area that treats people with frequency specific microcurrent. It does wonders for pain, particularly migraine/neuro-dysfunction.
You can also look into HBOT, but insurance won’t cover it in the states. When I did it for my TBI, the practice i went to was in the process of writing up a case study of their techs getting their migraines cured after a handful of dives, lol.
The doctor was able to tell the pharmacy to take a $695 hit on selling a prescription to you on his say so?
Drug manufacturers/reps sometimes give coupons to doctors to give to patients so they can afford the medicine.
Yes this ^
I've been taking Aimovig for 2 years now. It sounds like Ajovy as you take it once a month and it's about $700 an injection (in Canada). The listed side effects are not serious and I haven't had any issues yet. It is a miracle drug for me as I had daily migraines for 45 years. Now I get one or two a month. I was taking Sumatriptan daily and was concerned about the long term effects of that drug. Just like the Vax, I did a risk/benefit analysis on Aimovig and the benefits far outweighed the (known) risks. It has been a very positive experience for me so far but you never know what can happen long term. I suppose everything in life comes with risk.
Simple. Ask for the medicine, Get your own syringes Self administer
There’s absolutely no reason you can’t do this
It comes in an injection form already. Just have to take the top off and inject it myself at home. What I’m worried about is the medicine itself, it was originally put out by Pfizer.
Ozone Therapy. Juice fasting. Parasite cleanses. Edta chelation therapy.
https://pubmed.ncbi.nlm.nih.gov/11247184/
https://www.barnesandnoble.com/w/cure-for-all-diseases-hulda-regehr-clark/1103098922
Yeah I get that, I was hoping someone may have done more digging on this type of medicine ... monoclonal antibody. And that would know more about it.
The thing is I don’t Have to take this med if I don’t want to. I do have sumatriptan I can take also whether I take the injection or not.