True. Jefferson and George Washington were both against political parties. Washington argued that political parties needed to be restrained in a free country with a government empowered by the consent of the governed and established through popular elections. He warned of the possibility fearing they could distract the government from its required duty to the people and even lead to the eradication of the freedoms established by the founding.

This is what Washington had to say about parties in his Farewell Address in 1796 in which he noted the dangers of what he called the "spirit of the party":

The disorders and miseries which result gradually incline the minds of men to seek security and repose in the absolute power of an individual; and sooner or later the chief of some prevailing faction, more able or more fortunate than his competitors, turns this disposition to the purposes of his own elevation, on the ruins of public liberty.

Without looking forward to an extremity of this kind (which nevertheless ought not to be entirely out of sight), the common and continual mischiefs of the spirit of party are sufficient to make it the interest and duty of a wise people to discourage and restrain it.

It serves always to distract the public councils and enfeeble the public administration. It agitates the community with ill-founded jealousies and false alarms, kindles the animosity of one part against another, foments occasionally riot and insurrection. It opens the door to foreign influence and corruption, which finds a facilitated access to the government itself through the channels of party passions. Thus the policy and the will of one country are subjected to the policy and will of another.

Also George Mason, Patrick Henry refused to sign the Constitution because they felt it gave the central government too much power.