Yeah, u/HenryTheRed is right bang on target. Worst advil will do at a low OD is probably an ulcer, while the same low OD of acetaminophen /paracetamol will fuck up your life in a serious way. It's why I try not to use it as a pain relief anymore.
Seriously, tylenol can fuck a person up with low OD ratios, and with what these tiktok challenge morons are probably doing it's more Darwin award time than "oh they'll be fine". If the idiot in question who did this didn't seek medical attention within 8 hours via a NAC injection, her risk of dying rather horribly is very high.
24g of Paracetamol is generally accepted to be a fatal dose. The lowest amount of Paracetamol to cause death was found by one study to be 10g.
10g is 20 tablets. 24g is 48 tablets.
Henry is wrong about adult liver failure doses.
These morons were eating handfuls cause "Orange man bad"
Henry is still right to be cautious and it certainly seems like anyone pregnant should never take it. Maybe they will take it off the market now, who knows, but nobody is dying from taking 4 tablets.
Small doses over the recommended amount can kill you.
Only 2x over for Tylenol could fuck you up. Ibuprofen is 8x higher. It does verify from person to person. Maybe due to liver damage already done via drinking.
The radio show is full of examples of low doses killing people. These women were taking handfuls of these.
I am just reading you the allowed doses straight off the packet. It's not good idea to have more than the recommended amount as these women demonstrate but you are overstating the drugs lethality.
With regard to non pregnant adults and liver failure:-
"The toxic dose of paracetamol is highly variable. In general the recommended maximum daily dose for healthy adults is 4 grams.[17][18] Higher doses lead to increasing risk of toxicity. In adults, single doses above 10 grams or 200 mg/kg of bodyweight, whichever is lower, have a reasonable likelihood of causing toxicity.[19][20] Toxicity can also occur when multiple smaller doses within 24 hours exceed these levels. Studies have shown significant hepatotoxicity is uncommon in patients who have taken greater than normal doses over 3 to 4 days.[23] In adults, a dose of 6 grams a day over the preceding 48 hours could potentially lead to toxicity,[20] while in children acute doses above 200 mg/kg could potentially cause toxicity.[24]
24g of Paracetamol is generally accepted to be a fatal dose. The lowest amount of Paracetamol to cause death was found by one study to be 10g.
You should actually listen to the story I posted and how the Pharma company was waiting on the FDA to update dosage labels. Then the FDA said the Pharma could have done that on their own years ago.
Same with labeling for liver damage.
Anything above 3 grams per day of acetaminophen could potentially kill you. Near the end of the story.
This has actually been known since 2013
Use Only as Directed
https://www.thisamericanlife.org/505/use-only-as-directed
Tylenol is deadly at only a couple extra pills over the recommended amount. I think 2 to 4 in 24 hours is safe. 6 or more can be deadly.
You can shut your kidneys down with Advil (or just about anything) if you take too much
Yes, at 8 or 10x the recommended dose.
Only 2x for acetaminophen.
Yeah, u/HenryTheRed is right bang on target. Worst advil will do at a low OD is probably an ulcer, while the same low OD of acetaminophen /paracetamol will fuck up your life in a serious way. It's why I try not to use it as a pain relief anymore.
Seriously, tylenol can fuck a person up with low OD ratios, and with what these tiktok challenge morons are probably doing it's more Darwin award time than "oh they'll be fine". If the idiot in question who did this didn't seek medical attention within 8 hours via a NAC injection, her risk of dying rather horribly is very high.
24g of Paracetamol is generally accepted to be a fatal dose. The lowest amount of Paracetamol to cause death was found by one study to be 10g.
10g is 20 tablets. 24g is 48 tablets.
Henry is wrong about adult liver failure doses.
These morons were eating handfuls cause "Orange man bad"
Henry is still right to be cautious and it certainly seems like anyone pregnant should never take it. Maybe they will take it off the market now, who knows, but nobody is dying from taking 4 tablets.
If you are talking about 500mg doses, you are allowed 2 tabs every 4-6 hours, up to 8 in a 24 hour period.
Small doses over the recommended amount can kill you.
Only 2x over for Tylenol could fuck you up. Ibuprofen is 8x higher. It does verify from person to person. Maybe due to liver damage already done via drinking.
The radio show is full of examples of low doses killing people. These women were taking handfuls of these.
I am just reading you the allowed doses straight off the packet. It's not good idea to have more than the recommended amount as these women demonstrate but you are overstating the drugs lethality.
With regard to non pregnant adults and liver failure:-
"The toxic dose of paracetamol is highly variable. In general the recommended maximum daily dose for healthy adults is 4 grams.[17][18] Higher doses lead to increasing risk of toxicity. In adults, single doses above 10 grams or 200 mg/kg of bodyweight, whichever is lower, have a reasonable likelihood of causing toxicity.[19][20] Toxicity can also occur when multiple smaller doses within 24 hours exceed these levels. Studies have shown significant hepatotoxicity is uncommon in patients who have taken greater than normal doses over 3 to 4 days.[23] In adults, a dose of 6 grams a day over the preceding 48 hours could potentially lead to toxicity,[20] while in children acute doses above 200 mg/kg could potentially cause toxicity.[24]
24g of Paracetamol is generally accepted to be a fatal dose. The lowest amount of Paracetamol to cause death was found by one study to be 10g.
10g is 20 tablets. 24g is 48 tablets.
You should actually listen to the story I posted and how the Pharma company was waiting on the FDA to update dosage labels. Then the FDA said the Pharma could have done that on their own years ago.
Same with labeling for liver damage.
Anything above 3 grams per day of acetaminophen could potentially kill you. Near the end of the story.
--
Please prove me wrong and take 48 tablets.