Well I am talking about pharmacokinetic formulations which drive bioavailability and not chemical formulations but in terms of chemical formulations, here is some on B12.

1. Methylcobalamin

• Oral Bioavailability: Around 50–70% in individuals with normal gastrointestinal function. Methylcobalamin is better absorbed and retained in tissues compared to other forms, particularly for neurological benefits.

2. Hydroxocobalamin

• Oral Bioavailability: Approximately 40–70%, depending on the dose. Hydroxocobalamin is well-absorbed but tends to be more efficiently retained in the body compared to methylcobalamin, making it a good option for long-term storage and gradual release of B12.

As far as pharmacokinetics goes I will give an example using curcumin.

Absolute Bioavailability of Curcumin

• Oral Bioavailability: Extremely low (<1%) when consumed in its natural form. Curcumin undergoes extensive metabolism in the liver and intestinal walls, leading to poor plasma and tissue concentrations. Studies indicate that standard curcumin has very limited systemic availability after oral administration. Mainly due to its hydrophobic nature.

Enhancing Bioavailability with Liposomal and Nano Formulations

• Liposomal Formulations: Liposomes encapsulate curcumin in phospholipid bilayers, enhancing its absorption by improving solubility and protecting it from degradation. Liposomal curcumin can increase bioavailability by up to 8-10 times compared to standard curcumin.

• Nano Formulations: Nanoparticle-based delivery systems, such as nanomicelles or nanocurcumin, can enhance curcumin’s solubility, stability, and permeability. Nano-curcumin has been shown to increase its bioavailability around 40-fold in clinical studies, allowing for more effective therapeutic outcomes.

These advanced formulations bypass some of the limitations of curcumin’s natural form, offering more consistent therapeutic effects at lower doses.

The best form I have found is Nanocur. https://a.co/d/4NzSVqK I reached out to the company and recieved their pharmacokinetic and pharmcodynamic data, patents, etc. It's is a nano formulation wrapped in a beta-cyclodextrin complex. It's nearly 100% bioavailable. The size is 5nm which is amazingly small, a blood cell is roughly 6,000 yo 8,000 nm. Is almost small enough to passively pass through cells which is 1nm. So it still needs endocytosis to enter the cell, but it does so very well.

If you end up considering one or some of these phytochemicals and want a highly bioavailable brand just let me know, I also tend to reach out to companies like this and ask for their pharmacokinetic data.

Maybe I can make a site which will collate this information. But Unfortunately, this info is just from looking at a very long list of clinical data.

First thing to note is that phytochemicals have low bioavailability, using nano or liposomal formulations greatly enhance their clinical effects.

1. Phytochemicals with Combined Properties

A. Silymarin

• Source: Milk thistle (Silybum marianum)
• Diuretic Action: Enhances bile flow and supports kidneys in eliminating excess fluid, thereby reducing water retention.
• Antibiotic Activity: Exhibits antibacterial properties, particularly against Staphylococcus aureus and Escherichia coli.
• Hepatoprotective Properties: Stabilizes cellular membranes, reduces oxidative stress, and promotes liver regeneration. Used in treating cirrhosis, hepatitis, and fatty liver disease.

B. Berberine

• Source: Goldenseal (Hydrastis canadensis), Barberry (Berberis vulgaris)
• Diuretic Action: Enhances urine production and reduces water retention.
• Antibiotic Activity: Exhibits broad-spectrum antibacterial effects against Streptococcus pneumoniae, Staphylococcus aureus, Helicobacter pylori, and others.
• Hepatoprotective Properties: Reduces liver inflammation, oxidative stress, and lipid accumulation, showing benefits in non-alcoholic fatty liver disease (NAFLD) and hepatitis.

C. Curcumin

• Source: Turmeric (Curcuma longa)
• Diuretic Action: Promotes diuresis through kidney support and inflammation reduction.
• Antibiotic Activity: Effective against Escherichia coli, Staphylococcus aureus, and Candida albicans (antibacterial and antifungal properties).
• Hepatoprotective Properties: Reduces oxidative damage, inflammation, and fibrosis in liver cells, beneficial in NAFLD, alcoholic liver disease, and cirrhosis.

D. Green Tea Polyphenols (EGCG)

• Source: Green Tea (Camellia sinensis)
• Diuretic Action: Enhances kidney function and fluid excretion to reduce water retention.
• Antibiotic Activity: Effective against Helicobacter pylori and Staphylococcus aureus.
• Hepatoprotective Properties: Reduces fat accumulation, oxidative stress, and inflammation, useful in preventing liver disorders like NAFLD.

E. Gingerol

• Source: Ginger (Zingiber officinale)
• Diuretic Action: Promotes kidney function and reduces water retention, especially in the context of inflammation.
• Antibiotic Activity: Exhibits antimicrobial properties, particularly against Escherichia coli, Salmonella spp., and Candida albicans.
• Hepatoprotective Properties: Reduces inflammation, lipid peroxidation, and fibrosis in the liver, useful in toxin-induced liver injury and fatty liver disease.

2. Non-Phytochemical Supplements with Similar Properties

A. Taurine

• Diuretic Action: Acts as a mild diuretic, supporting fluid balance by enhancing kidney function.
• Antibiotic Activity: Though not directly an antibiotic, taurine supports immune function, helping to protect against bacterial infections.
• Hepatoprotective Properties: Reduces liver inflammation, fibrosis, and oxidative damage. Particularly useful in alcohol-induced liver damage and NAFLD.

B. N-Acetylcysteine (NAC)

• Diuretic Action: Indirect diuretic action by reducing oxidative stress and supporting kidney function.
• Antibiotic Activity: NAC disrupts biofilms, making it useful in conjunction with antibiotics for chronic bacterial infections.
• Hepatoprotective Properties: Boosts glutathione levels in the liver, reducing oxidative stress and improving liver detoxification. Used in acetaminophen toxicity and liver fibrosis.

C. Alpha-Lipoic Acid (ALA)

• Diuretic Action: Enhances kidney function and has mild diuretic effects.
• Antibiotic Activity: Possesses antimicrobial activity against some bacterial strains, particularly in reducing inflammation associated with infections.
• Hepatoprotective Properties: ALA is a potent antioxidant, protecting the liver from oxidative damage and promoting detoxification, especially in conditions like hepatitis and cirrhosis.

D. Vitamin E

• Diuretic Action: Supports fluid balance through its antioxidant effects, indirectly aiding kidney function.
• Antibiotic Activity: Though not an antibiotic, its immune-boosting properties help reduce infection risk.
• Hepatoprotective Properties: Vitamin E reduces oxidative damage in liver cells and has been studied in NAFLD and other liver conditions to reduce fibrosis and inflammation.

Prayers fren

• Please give me an update as to his condition.
• I would be happy to do some research on alternative treatment for his condition if it ends up being a chronic issue.

Did you hate Jesus's religion?

There are plenty of people here that are Jews that do not follow Talmud, nor are they from the same tribe. Also, if he were part of the tribe, he could still be innocent himself. I don't think he is personally, but indictments against an individual for the actions of a tribe is wrong.

They are actually lowercase "L"s

Im running a script to convert any lowercase into small caps.

THE NEW YORK A.G. USED A STATUTE TO GO AFTER ME THAT HAS NEVER BEEN USED BEFORE, NOT ONCE, FOR SUCH A PURPOSE. IT, IN AND OF ITSELF, IS SOOO UNCONSTITUTIONAL AND UNFAIR. UNDER THIS STATUTE, I GET NO JURY AND HAVE NO RIGHTS. Aʟʟ DECISIONS AND RIGHTS ARE GIVEN TO, IN THIS CASE, A CORRUPT, TRUMP HATING JUDGE, WHO CAME UP WITH A CRAZY, OUT OF THIN AIR AWARD, IN ORDER TO DAMAGE ME POLITICALLY, AND NOT ALLOW ME TO USE ANY OF THE LARGE AMOUNT OF CASH I HAVE BUILT UP OVER THE YEARS, THROUGH HARD WORK, INSIGHT, INSTINCT, AND DILIGENCE, ON MY POLITICAL CAMPAIGN FOR PRESIDENT. THAT IS JUST WHAT CROOKED JOE BIDEN WANTED THIS POLITICAL HACK, COUPLED WITH A CORRUPT AND RACIST ATTORNEY GENERAL, TO DO. I DID NOTHING WRONG! THIS IS SIMPLY A “TAKING.” MUCH LIKE WHAT IS DONE IN COMMUNIST COUNTRIES, AND WILL LEAVE AN IRREPARABLE STAIN ON NEW YORK STATE AND ITS JUDICIAL SYSTEM. IT IS TOTALLY UNCONSTITUTIONAL, INCLUDING THE HARSH GAG ORDER IMPOSED. THE STATUTE OF LIMITATIONS WAS ALREADY RULED ON, FOR ME!

Get to know your local farm. I get raw milk and uncleaned eggs from them

Yeah pretty gross. I watch Muslim debates about 4 hours every week day

True, but there is no minimum age in Islam. Only restriction is that if you have sex with the Lil babies, you have to wait 3 months (no sex) till you divorce them. (Iddah/ waiting period)

Nah, aisha was 6 when he married her. He waited like a gentleman till she was 9 and still playing with dolls to consummate lmao.

They lookin for some aisha girls

Have you acknowledged anything I've asked? Or have you instead given a red herring, evasion, ad hominem?

• I opened the page you sent about Jesus being a myth. Unfortunately for that idea, not a single employed biblical scholor would agree. Even the athiest Bart Ehrman conceded that Jesus existed.

• Sataniss are the enemy yes. Regardless of if satan exists. But If satan himself exists, satan is the enemy as well. All I know is that if I was satan and I wanted to take the souls of as many as I could, I would make false religions, and false theologies like Jesus being a myth so people feel good about living without knowing Jesus and without being saved.

Not sure why but you seem to be projecting an attitude on to me. Honestly, you just seem confused or something. I was just clarifying that you do fall into one of those categories. Materialism is the hardest one to defend, platonism or deism is likely the easiest.

I'm not trying to.

• a materialist (nothing but the physical universe)
• a platonist (logical/conceptual universe alongside the material universe)
• a universal naturalist. (Non God, non intelligent, creator which is spaceless and timeless.)
• a diest. (God exists but is impersonal)
• a theist (God exists and is personal) There is nothing left. If you say you aren't any of them, you are just confused.

Red herring

So did my father, he now has stage 4 lung cancer.

If you are an athiest materialist, then the picture is accurate. Are you a platonist? Or are you a philosophical naturalist or cosmic naturalist?

It's not for me.

My favorite type of Jew is messianic jew :). jewish christians

This is a misunderstanding. Sterilizing immunity refers to the type of immune response where the immune system completely eliminates a pathogen from the body, preventing the pathogen from replicating or establishing infection. With sterilizing immunity, the person not only avoids getting sick but also does not carry or spread the pathogen to others.

• I enjoy researching this stuff.
• That's fine, have them then possibly go on a modified "Low FODMAP" diet. In the end avoid highly processed foods, only shop on the outer edges of grocery stores, avoid seed oils.