"Another study found no toxicity in humans receiving 1 g/kg/day of DMSO (about 34 fluid ounces for a 70 kg person) for 12 weeks." From the 'how many ounces a day of DMSO becomes toxic'.

From the 'If I use applications of DMSO on one arm can the DMSO work anywhere else?' says putting it on one arm and it will spread all over. It's a solvent with super penetrating capabilities. It can carry medications past the blood brain barrier. It will go everywhere.

I bought the bottle listed at the top. It has an eyedropper several inches long. I take mine orally. I take about one inch worth three times a day. The taste is so bad I pour about 2 oz of grape juice in the glass just to kill the taste. That's a lot of dilution. Its helping my eyes, my ears, and is helping with memory and brain fog. I'm 75. I have been using this stuff for only 3 weeks now. Its said to be good for the skin, maybe it will help with the veins. A small recent scar is gone. I expected it might go away next year on its own.

Overall expect it to work. It might take a couple months. The small amount is helping me more than expected. One day I took twice as much and noticed the smell they talked about so I stopped that. As always, start small and go from there. Don't be afraid of this stuff. Its great medicine.

I found this video very useful. It's an interview with a doctor who uses it in his practice, not too long, and interesting. https://rumble.com/v6sfbob-natures-cure-the-miracle-drug-big-pharma-fears-daily-pulse-ep-9.html Hope it helps.

From another thread-

I'll try to be more clear. At the advice of a naturopath, I took 30 ml pure liquid DMSO mixed with 30 ml distilled water, mixed in a glass jar with a metal spoon. You just swallow it. You may want a chaser because it tastes horrible. I was on no other medications so I can't speak to that, like taking them apart from each other. I took this everyday for a few months. I started at 5 ml to see how I'd handle it and moved up to 30 ml in just a couple days. I'm a fairly big guy, 220lbs, so your milage may vary. For topical use a gel is easier because liquid DMSO runs off like water. You can buy this gel ready made at your local farm store in the horse section. Here's a link https://www.ruralking.com/dmso-90-gel-16-0z You just rub it on to areas you want help. Make sure your skin is clean and rub it on with a cotton ball, nothing artificial like polyester. Let it dry before putting clothing over it and same deal, cotton clothing. You can apply it as many times as a day as your need. It works great for pain Read this stack for uses but it helps with a wide variety of things. All you can do is give it a shot and see if it helps. You're not going to find things that say x dose applied x way cures x problem. It's not FDA approved so all you're going to find is anecdotes of how people used it and what it did.

I agree. Very difficult to find out dosing recommendations. The below is from another thread about using DMSO.

(I am only taking 2 teaspoons with a small amount of water in the morning so just once a day and do notice an improvement in eyesight. People take much higher doses though. They buy it by the gallon.)

"I'll try to be more clear. At the advice of a naturopath, I took 30 ml pure liquid DMSO mixed with 30 ml distilled water, mixed in a glass jar with a metal spoon. You just swallow it. You may want a chaser because it tastes horrible. I was on no other medications so I can't speak to that, like taking them apart from each other. I took this everyday for a few months. I started at 5 ml to see how I'd handle it and moved up to 30 ml in just a couple days. I'm a fairly big guy, 220lbs, so your milage may vary. For topical use a gel is easier because liquid DMSO runs off like water. You can buy this gel ready made at your local farm store in the horse section. Here's a link https://www.ruralking.com/dmso-90-gel-16-0z You just rub it on to areas you want help. Make sure your skin is clean and rub it on with a cotton ball, nothing artificial like polyester. Let it dry before putting clothing over it and same deal, cotton clothing. You can apply it as many times as a day as your need. It works great for pain Read this stack for uses but it helps with a wide variety of things. All you can do is give it a shot and see if it helps. You're not going to find things that say x dose applied x way cures x problem. It's not FDA approved so all you're going to find is anecdotes of how people used it and what it did."