Explanation. The mRNA has a region known as 3'UTR (3 prime Untranslated Region) which contains sequences that are not used for encoding any proteins but just acts as regulatory area. Think of it as an extra code beyond whats required for coding the Spike Protein.
Someone took the 3'UTR sequence from the Pfizer's mRNA vaccine, and searched it against the human genome and found a matching strand in the Mitochondrial region.
When the mRNA vaccine teaches the body to attack the spike protein, what happens of the body notices this 3'UTR sequence and learns to attack it as well?
Now our immune system has been primed against our own mitochondrial RNA. If it so happens that the immune system recognises this RNA as an "enemy" our immune system can turn against our own body - aka Auto Immune.
If it's a non-coding region, it won't be expressed in the spike protein, and won't trigger an immune response. It appears this sequence is only in the mRNA used to co-opt cells to produce spike proteins but the sequence itself doesn't trigger an immune response.
Your immune system doesn't develop a defense against all of the other human DNA floating around in your system (yes yes, auto-immune conditions exist but for many other complicated reasons) and this is just one tiny sequence inside the vaccine.
I agree with your assessment of the "immune system" as we generally understand it; this UTR is on the mRNA and will not encounter the anti-bodies that float around between cells, in the blood, etc. looking for problems. They are separated by very well defined barriers. If that were not the case, multicellular life could not exist.
However, there are other types of "immune systems." CRISPR-Cas9 as a gene editing tool was found precisely because bacteria use it as an intracellular immune system. And CRISPR is not the only one. We have intracellular immune systems in our own cells. This mRNA could possibly cause problems with such systems. In fact the exposure of parts of the interior of the mitochondria into the cytosol is a common signal for autophagocytosis (take out the trash) or apoptosis (kill the cell).
There are several assumptions in there, but it isn't without theoretical backing (and substantial experimental backing in other organisms). This is potentially something to be concerned about.
Just wondering, is there an immune response to the vaccine itself? (rather than just to the spike proteins it produces) - I hate calling it a vaccine as it is not one.
Can I ask what position you were in? I assume having non-unique human sequence in PCR would give false positives correct? I remember hearing a lot about it, but it was never conclusive because there was no authoritative source for the primer used in PCR
furin site codon switch issue (can elaborate if needed)
Please do, I am interested in learning.
Also, to the extent you can share this without doxxing yourself, I strongly encourage making a top level post. At the very least, the Covid money and the ways they discourage people from questioning / dissent etc. I know GAW has grown and we have lot of people here now with first hand experience of all this. All this needs to be heard by people.
In other words they are tricking your body into killing itself. They might as well hand you a double barrel shotgun to play Russian rue-let with. Can we please exterminate these lunatics now?
Makes you think right? If Trump exposed the election fraud before Jan 20 or even caught them all red handed on Nov 3rd, none of this would have happened and all these genocidal maniac would head to the matresses to come back with this plan if not a year later, a decade later.
There is some question about whether millions really died because of HIV or they died because Fauci forced them to inject toxins like AZT as "treatment" much like he is now doing with Remdesivir and Gene therapy
Explanation. The mRNA has a region known as 3'UTR (3 prime Untranslated Region) which contains sequences that are not used for encoding any proteins but just acts as regulatory area. Think of it as an extra code beyond whats required for coding the Spike Protein.
Someone took the 3'UTR sequence from the Pfizer's mRNA vaccine, and searched it against the human genome and found a matching strand in the Mitochondrial region.
When the mRNA vaccine teaches the body to attack the spike protein, what happens of the body notices this 3'UTR sequence and learns to attack it as well?
Now our immune system has been primed against our own mitochondrial RNA. If it so happens that the immune system recognises this RNA as an "enemy" our immune system can turn against our own body - aka Auto Immune.
This paper may be related to that. See Figure 1 which seems to show the highest antibody cross-reactivity with mitochondria.
Potential antigenic cross-reactivity between SARS-CoV-2 and human tissue with a possible link to an increase in autoimmune diseases
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7246018/ https://web.archive.org/web/20211119151847/https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7246018/
Oh. No.
If it's a non-coding region, it won't be expressed in the spike protein, and won't trigger an immune response. It appears this sequence is only in the mRNA used to co-opt cells to produce spike proteins but the sequence itself doesn't trigger an immune response.
Your immune system doesn't develop a defense against all of the other human DNA floating around in your system (yes yes, auto-immune conditions exist but for many other complicated reasons) and this is just one tiny sequence inside the vaccine.
I agree with your assessment of the "immune system" as we generally understand it; this UTR is on the mRNA and will not encounter the anti-bodies that float around between cells, in the blood, etc. looking for problems. They are separated by very well defined barriers. If that were not the case, multicellular life could not exist.
However, there are other types of "immune systems." CRISPR-Cas9 as a gene editing tool was found precisely because bacteria use it as an intracellular immune system. And CRISPR is not the only one. We have intracellular immune systems in our own cells. This mRNA could possibly cause problems with such systems. In fact the exposure of parts of the interior of the mitochondria into the cytosol is a common signal for autophagocytosis (take out the trash) or apoptosis (kill the cell).
There are several assumptions in there, but it isn't without theoretical backing (and substantial experimental backing in other organisms). This is potentially something to be concerned about.
I wouldnt say the probablility is 0. Definitely small, but non-zero.
Please see my response to this statement.
Just wondering, is there an immune response to the vaccine itself? (rather than just to the spike proteins it produces) - I hate calling it a vaccine as it is not one.
This knowledge was available May 2020, I think it was Sherri Tenpenny that made a video about it.
They’ve been talking about the CGG-CGG sequence for over a year. I think it fits into this larger sequence.
Can I ask what position you were in? I assume having non-unique human sequence in PCR would give false positives correct? I remember hearing a lot about it, but it was never conclusive because there was no authoritative source for the primer used in PCR
Please do, I am interested in learning.
Also, to the extent you can share this without doxxing yourself, I strongly encourage making a top level post. At the very least, the Covid money and the ways they discourage people from questioning / dissent etc. I know GAW has grown and we have lot of people here now with first hand experience of all this. All this needs to be heard by people.
In other words they are tricking your body into killing itself. They might as well hand you a double barrel shotgun to play Russian rue-let with. Can we please exterminate these lunatics now?
1776
Makes you think right? If Trump exposed the election fraud before Jan 20 or even caught them all red handed on Nov 3rd, none of this would have happened and all these genocidal maniac would head to the matresses to come back with this plan if not a year later, a decade later.
AIDS. Fauci killed millions with HIV and now many more millions will die from AIDS caused by the vaccine.
There is some question about whether millions really died because of HIV or they died because Fauci forced them to inject toxins like AZT as "treatment" much like he is now doing with Remdesivir and Gene therapy