I’ve done both but this particular time, I used it topically. Husband and I had been doing horse paste prophylactically. I knew it was cancer but I had no intention of going to a doctor or hospital, no trust there anymore. Incidentally I was a nurse for over thirty years.
There is an alternative to surgery, and the potential for follow-up plastic surgery. If your mom is especially concerned about surgery, and depending upon the actual location, Efudex is a possibility as well. But to imply that Efudex is "easier" is far from the truth. It causes the worst burn you can ever imagine, and the cancer cells are metabolized in such a way that they destroy themselves and eventually flake off. The whole process can take 6-8 weeks. But when you're done, the skin is like a baby's.
Efudex is most often prescribed when a face (or other part of the body) is covered with too many actinic keratoses to treat separately. There is a new formulation of the cream which adds vitamin D, and works more quickly and aids in the healing, too.
Many supplements, including almost every fruit and vegetable extract, fight cancer.
Curcumin, quercetin, resveratrol (which works well topically for melanoma; don't know how it would do for what your mom has), etc etc. A Supplement may be known for only ONE thing (e.g., cranberry fights urinary infections) but in almost all cases the supplement will have ADDITIONAL benefits including, typically, fighting cancer at one or more stages -- cranberry in fact has been shown in studies to fight cancer, for example. Poke around, you'll see what I mean. It's APPALLING how this has all been swept under the rug in favor of toxic chemical "therapies" and other harmful-if-sometimes-helpful approaches.
Don't forget immune-system boosters, especially if your mom has had (or will have) chemo, which greatly weakens the immune system, or has been jabbed, which is even worse. You NEED your immune system working well if you have cancer.
Were it me, I'd be taking a LOT of those things, starting with curcumin, which appears to be the apex predator when it comes to cancer. Hundreds, more likely THOUSANDS of studies supporting it. Be smart, do some research, watch the dosing, and so on, but there is good evidence that an intense regimen of carefully chosen supplements (plus good diet, some exercise, etc) will improve the odds against cancer and probably improve the quality of life as well.
I don't have time to dig out links right now but here's a good place to start: Life Extension's Protocol page. It's not the final word on things but a solid, curated place to start.
Best wishes to your mom for a swift and complete recovery. She's fortunate to have you looking out for her.
I’ve used it to treat facial basal and squamous cell carcinomas. It’s inexpensive and it works. The only downside is treatment times are somewhat unpredictable because it works to seek out and destroy the entire cancer, which is often like an iceberg where what’s visible at the surface is just a fraction of the whole lesion. Start to end treatment times will last from a few weeks to a few months depending on the size of the lesion.
The good news is it has no effect on normal cells, so unlike surgery it doesn’t involve removing good cells with the bad ones. The result is cosmetically superior to Mohs or other surgical methods and involves no risk of requiring plastic surgery to “clean up” after the cancer surgery. When finished it’s as if the cancer never existed and even your dermatologist will not notice the treated areas unless they really look hard.
There’s a support group for the product and its users on Facebook, which is the only time I’ve ever found a use for that service.
A good doctor or clinic skilled in Mohs procedure will be a great benefit. Only as invasive as the cancer itself. They remove the cancer carefully, taking only as much tissue as needed and testing for cancer presence or lack thereof before proceeding further. The skill of the doctor when it comes to reconstructive surgery is an important factor to consider. There are 3 types of skin cancer. Basal cell, which is very localized, squamous, which is local in nature but can spread to nearby tissue at a faster rate, and melanoma which can spread to other organs and be devastating.
I, personally have had 7 basal cell cancers and one melanoma removed. My sisters have had more than myself, of all three kinds. We were all children of the sun growing up in Texas in the early 60's. It is not a pleasant experience, but it is not horrible. The removal is far simpler than the reconstructive surgery. Early detection is key. A skilled reconstructive surgeon is worth their weight in gold.
I unknowingly let mine get worse, unaware what they were. My sister finally convinced me to seek help. The doctor has to remove the cancerous tissue as far as it leads. I was lucky. I had most of the bottom right quarter of my nose and a dime sized part of my left ear removed. I also had smaller ones on my upper lip and left eyelid removed. The reconstructive surgery was not pleasant, but I must admit was not terribly painful. All done with local anesthetics. Two months later, you would never know anything had ever even happened. The first two weeks I looked like somebody beat the crap out of me.
If you have a persistent sore or what appears to be a pimple or boil that just won't go away, get to a dermatologist. Sooner is better.
Supplement use and risk of cutaneous squamous cell carcinoma
Maryam M Asgari et al. J Am Acad Dermatol. 2011 Dec.
Background: Laboratory and epidemiologic studies suggest that certain dietary supplements may alter risk of cutaneous squamous cell carcinoma (SCC).
Objective:
We sought to examine the association between supplement use and SCC risk.
Methods:
Cases (n = 415) were defined as Kaiser Permanente Northern California members with a pathology-verified SCC in 2004 and control subjects (n = 415) were age-, sex-, and race-matched members with no history of skin cancer. Supplement use and SCC risk factors were ascertained by questionnaire. Associations of SCC with use of multivitamins; vitamins A, C, D, and E; and grape seed extract were estimated as odds ratios and 95% confidence intervals using conditional logistic regression. Models were adjusted for SCC risk factors and other supplement use.
Results:
Grape seed extract users had a significantly decreased risk of cutaneous SCC (adjusted odds ratio 0.26, confidence interval 0.08-0.89, P = .031). Multivitamin use was associated with a borderline significant reduction in SCC risk (adjusted odds ratio 0.71, confidence interval 0.51-1.00, P = .049). Use of vitamins A, C, D, and E was not associated with SCC risk.
Limitations:
The data may be prone to recall and selection bias because of the case-control design. No information was obtained on dose or duration of supplement use.
Conclusions:
Use of grape seed extract may be associated with a decreased risk of cutaneous SCC. The other supplements included in our study did not reveal clear associations with SCC risk.
Solanum incanum extract (SR-T100) induces human cutaneous squamous cell carcinoma apoptosis through modulating tumor necrosis factor receptor signaling pathway
Chin-Han Wu et al. J Dermatol Sci. 2011 Aug.
Background:
The Solanum species herbs have been used to treat cancer for centuries; however, the underlying mechanisms and effectiveness in vivo remain unclear.
Objectives:
SR-T100, extracted from the Solanum incanum, contains solamargine alkaloid as the main active ingredient. Here, we investigated the apoptosis-inducing effects of SR-T100 for targeting squamous cell carcinoma (SCC) in vitro and in vivo.
Methods:
We elucidated the mechanism by which SR-T100 induces apoptosis of human SCCs (A431, SCC4, SCC9, and SCC25) cells. The efficacy and safety issues were addressed regarding topical treatment of SR-T100 on UVB-induced cutaneous SCC of hairless mice and actinic keratoses (AKs) of human.
Results:
SR-T100 induces apoptosis in human SCCs cell lines by up-regulating the expressions of tumor necrosis factor receptors (TNFRs) and Fas, and downstream adaptors FADD/TRADD of the TNF-α and Fas ligand signaling cascades. SR-T100 also triggered the mitochondrial apoptotic pathway, as up-regulated cytochrome c and Bax, down-regulated Bcl-X(L). Animal experiments showed that all papillomas (35/35) and 27 of 30 UVB-induced microinvasive SCCs in hairless mice disappeared within 10 weeks after once-daily application of topical SR-T100. Furthermore, 13 patients, who suffered with 14 AKs, were treated with once-daily topical SR-T100 gel and 10 AKs cured after 16 weeks, showing negligible discomforts.
Conclusion:
Our studies indicate that SR-T100 induces apoptosis of SCC cells via death receptors and the mitochondrial death pathway. The high efficacy of SR-T100 in our preclinical trial suggests that SR-T100 is a highly promising herb for AKs and related disorders.
Anti-skin cancer properties of phenolic-rich extract from the pericarp of mangosteen (Garcinia mangostana Linn.)
Jing J Wang et al. Food Chem Toxicol. 2012 Sep.
Skin cancers are often resistant to conventional chemotherapy. This study examined the anti-skin cancer properties of crude ethanol extract of mangosteen pericarp (MPEE) on human squamous cell carcinoma A-431 and melanoma SK-MEL-28 lines. Significant dose-dependent reduction in% viability was observed for these cell lines, with less effect on human normal skin fibroblast CCD-1064Sk and keratinocyte HaCaT cell lines. Cell distribution in G(1) phase (93%) significantly increased after 10 μg/ml of MPEE versus untreated SK-MEL-28 cells (78%), which was associated with enhanced p21(WAF1) mRNA levels. In A-431 cells, 10 μg/ml MPEE significantly increased the sub G(1) peak (15%) with concomitant decrease in G(1) phase over untreated cells (2%). In A-431 cells, 10 μg/ml MPEE induced an 18% increase in early apoptosis versus untreated cells (2%). This was via caspase activation (15-, 3- and 4-fold increased caspse-3/7, 8, and 9 activities), and disruption of mitochondrial pathways (6-fold decreased mitochondrial membrane potential versus untreated cells). Real-time PCR revealed increased Bax/Bcl-2 ratio and cytochrome c release, and decreased Akt1. Apoptosis was significantly increased after MPEE treatment of SK-MEL-28 cells. Hence, MPEE showed strong anti-skin cancer effect on these two skin cancer cell lines, with potential as an anti-skin cancer agent.
Grape seed proanthocyanidines and skin cancer prevention: Inhibition of oxidative stress and protection of immune system Santosh K. Katiyar Abstract Overexposure of the skin to ultraviolet (UV) radiation has a variety of adverse effects on human health, including the development of skin cancers. There is a need to develop nutrition-based efficient chemopreventive strategies. The proanthocyanidins present in grape seeds (Vitis vinifera) have been shown to have some biological effects, including prevention of photocarcinogenesis. The present communication discusses the in vitro and in vivo studies of the possible protective effect of grape seed proanthocyanidins (GSPs) and the molecular mechanism for these effects. In SKH-1 hairless mice, dietary supplementation with GSPs is associated with a decrease of UVB-induced skin tumor development in terms of tumor incidence, tumor multiplicity, and a decrease in the malignant transformation of papillomas to carcinomas. It is suggested that the chemopreventive effects of dietary GSPs are mediated through the attenuation of UV-induced: (a) oxidative stress; (b) activation of mitogen-activated protein kinases and nuclear factor-κB signaling pathways; and (c) immunosuppression through alterations in immunoregulatory cytokines. Collectively, these studies indicate protective potential of GSPs against experimental photocarcinogenesis in SKH-1 hairless mice, and the possible mechanisms of action of GSPs, and suggest that dietary GSPs could be useful in the attenuation of the adverse UV-induced health effects in human skin.
Chemoprevention of lung and skin cancer by Beta vulgaris (beet) root extract
G J Kapadia et al. Cancer Lett. 1996.
Abstract
The in vitro inhibitory effect of Beta vulgaris (beet) root extract on Epstein-Barr virus early antigen (EBV-EA) induction using Raji cells revealed a high order of activity compared to capsanthin, cranberry, red onion skin and short and long red bell peppers. An in vivo anti-tumor promoting activity evaluation against the mice skin and lung bioassays also revealed a significant tumor inhibitory effect. The combined findings suggest that beetroot ingestion can be one of the useful means to prevent cancer.
Olive leaf extract and its main component oleuropein prevent chronic ultraviolet B radiation-induced skin damage and carcinogenesis in hairless mice
Yoshiyuki Kimura et al. J Nutr. 2009 Nov.
Chronic exposure to solar UV radiation damages skin, increasing its thickness and reducing its elasticity, and causes skin cancer. Our aim in this study was to examine the effects of an olive leaf extract and its component oleuropein on skin damage and the incidence of skin tumors caused by long-term UVB irradiation in hairless mice. Male hairless mice (5 wk old) were divided into 6 groups, including a non-UVB group, a vehicle-treated UVB group (control), 2 olive leaf extract-treated UVB groups, and 2 oleuropein-treated UVB groups. Five groups were UVB irradiated (36-180 mJ/cm(2)) 3 times each week for 30 wk and skin thickness and elasticity after UVB irradiation were measured every week. Olive leaf extract (300 and 1000 mg/kg) and oleuropein (10 and 25 mg/kg) were administered orally twice daily every day for 30 wk. The extract and oleuropein significantly inhibited increases in skin thickness and reductions in skin elasticity, and skin carcinogenesis and tumor growth.(cont.)
Molecular mechanism of apoptosis induction in skin cancer cells by the centipedegrass extract
2013
Srilatha Badaboina et al. BMC Complement Altern Med.
Background: Centipedegrass extract (CGE) is mainly composed of maysin and its derivatives, which are recognized internationally as natural compounds. Compared to other flavonoids, maysin has a unique structure in that mannose is bound to the flavonoid backbone. CGE exhibits some biological properties in that it can function as an anti-oxidant, anti-inflammatory, anti-adipogenic, and insecticidal. Whether CGE has other biological functions, such as anti-cancer activity, is unknown.
Methods: B16F1 (mouse) and SKMEL-5 (human) cells were treated with CGE, and their subsequent survival was determined using MTT assay. We performed a cell cycle analysis using propidium iodide (PI), and detected apoptosis using double staining with annexin V-FITC/PI. In addition, we examined mitochondrial membrane potentials using flow cytometry, as well as signaling mechanisms with an immunoblotting analysis.
Results: CGE inhibited skin cancer cell growth by arresting the cell cycle in the G2/M phase, and increased both early and late apoptotic cell populations without affecting normal cells. Furthermore, we observed mitochondrial transmembrane depolarization, increased cytochrome-c release, caspase-3 and caspase-7 activation, and increased poly ADP-ribose polymerase degradation. CGE also downregulated activation of p-AKT, p-glycogen synthase kinase-3β (GSK-3β), and p-BAD in a time-dependent manner. LY294002 inhibition of phosphoinositide 3-kinase (PI3K) significantly sensitized skin cancer cells, which led to an increase in CGE-induced apoptosis.
Conclusions: CGE controlled skin cancer cell growth by inhibiting the PI3K/AKT/GSK-3β signaling pathway and activating the effector caspases. This study is the first to demonstrate anti-cancer properties for CGE, and that CGE may be an effective therapeutic agent for treating skin cancer.
Durable response of cutaneous squamous cell carcinoma following high-dose peri-lesional injections of Viscum album extracts--a case report
2013
Case Reports
Paul Georg Werthmann et al. Phytomedicine.
Background:
Cutaneous squamous cell carcinoma (CSCC) is a common locally invasive skin cancer which rarely metastasises. First-line treatment is surgical excision, which is curative in most cases. Viscum album extract (VAE) is a widely used herbal cancer treatment with cytotoxic, apoptogenic and immunological effects, but has not been investigated in CSCC.
Case presentation:
A 78-year-old patient with histologically diagnosed CSCC refused surgical excision and was treated with peri-lesional high-dose VAE. After 10 months of treatment the CSCC had disappeared clinically. The patient has been recurrence-free for 4 years.
Conclusion:
The presented case shows clinical response of a CSCC to high-dose peri-lesional VAE injections. Further research on VAE in CSCC is warranted.
Cutting often results in disfiguration [I have known a couple of people who had skin cancer and their "after" results were terrible] and it still returns-- maybe get a second opinion from an alternative/holistic practitioner including diet changes, juicing greens and fruit, baking soda, raw apple cider vinegar, apricot seeds, someone even used prid, there are a number of possibilities. I myself have fair skin and had damaged areas and scars on my face and chest, and after a few years of eating mostly raw organic fruits greens and veggies my skin is now soft and pretty good for 60+.
Look to see if there is a MOHS surgeon around. This would be the best way to remove the cancer. I am not a medical person, but I am familiar with this problem.
Hey Yomammasayshi - Question for you - have the docs tried cryotherapy with liquid nitrogen on the cancerous spot? I am a stage III survivor and whenever I get any kind of raised or textured spot, freckle or lump on my skin anywhere since my diagnosis four years ago, I simply buy a canister or two of Dr. Scholl's Freeze Away liquid nitrogen and freeze the spot until I am sure it has been fully frozen (as little as 20 seconds to 1 minute). Soon the spot swells and blisters and scabs and heals and about two weeks later, the thing is GONE.
If I keep the spot out of the sun during healing there is no scar at all. It's fantastic. Freezing it will kill it down to its roots and no trauma or disfigurement will result to the area, unlike if she has a big divot cut out by the doc. Surgeons live to 'cut'. They'll take a nice big gouge of flesh and leave a big wound in her body in order to justify their expensive education. Freezing is by far the better solution.
If by chance any of the cancer appears to still be detectable after the first freeze, you simply hit it again. I had a thick painful lump in my calf that I had to freeze about 6 times over the course of a week, and that did the trick. A small freckle-sized spot usually is killed on the first attempt.
The Dr. Scholl's product is identical process to what the dermatologists use in their practice. If she can reach it herself it is easy to do yourself. If not, employ a sensitive family member to do it for her in the comfort of her own home.
I am available for questions if she has any.
Here's an article on the subject:
Treating Squamous Cell Carcinoma - American Cancer
Cryotherapy
(Or cryosurgery) is used for some early squamous cell cancers, especially in people who can't have surgery, but is not recommended for larger invasive tumors or those on certain parts of the nose, ears, eyelids, scalp, or legs.
I had squamous cell carcinoma on the inside of my cheek. Before the Chy-an virus, my doctor prescribed HCQ after a quick laser surgery. In total remission now.
Get the surgery. I had one on my hand and had it taken off. It was deep and left a about three inch scar because I let it get so large the surgeon had to put a lot of skin to close the gap, and that meant a lot longer scar.
The scar has faded to the point it isn't very noticeable. With a scar on her face they might be able to do some cometic surgery to hide it. It will depend on the size of the cancer how intrusive they have to be.
Wow, so much good information here. I will add my anecdotal experience. About 10 years ago, I got what looked like a small skin cancer on my arm. I immediately began taking grape seed extract and turmeric (watch the dosage, they are both blood thinners) and ate only vegetables. Wish I had known about ivermectin, but I made a poultice of coconut oil, baking soda, and salt and applied that 3x a day. As the spot shrank, I began to be a little more aggressive and scrubbed it daily with the poultice. (I would be hesitant to scrub in the facial area). In six weeks, it was completely gone and I was left with a smooth white spot. Some time later, my husband developed a spot that looked exactly like the one I had and his was confirmed to be SCC. If another pops up, however, I will definitely check into the curaderm.
Generally sun on face causes basal cell carcinomas. Squamous cell is usually on the lower lip. I assume an incisional biopsy was done if you are reporting it as squamous cell. Those are more aggressive and widely excised. Don't fool around and follow the advice of the surgeon after the pathology report is received.
Rick Simpson method cannabis oil watch his videos, very simple to make, use topically can also try coconut oil soaked in cannabis. my friend used black slave (Balck Slave is Indian blood root and a caustic powder) on his skin cancer for many years, Arms, face and ears, it would turn into a open wound and pop out a hard white looking glob, then he had to heal the wound, He switched to the Cannabis oil, it just vanished in a few days to a week using rick Simpson cannabis oil homemade. The Simpson oil is cannabis soaked in alcohol then cook off the alcohol, what remains is a black tar oil.
I know a fella that makes it as well he has a website, he uses grape seed oil infused cannabis soaked for two to three months. topically or ingested. not heated so most folks that eat it do not get high. you can also just soak cannabis oil in Coconut oil.
Coconut oil is non inflammatory wile grape seed oil is inflammatory.
it does work for most people, we used to make gobs and give irt away.
I have a friend that soaked his cannabis in Everclear 190 proof and uses it topically for all kinds of pain issues, he's given over 300 roll-on bottles away.
There was a lady on here that used ivermectin horse paste for her mother topically as well but it wasn't skin cancer... she posted her mother's blood work to prove it. I do not recall the type of cancer she had though.
Good Luck Pray Hard.
This is called the MOHS technique. I had it done when I had eye cancer, and had to have part of my eyelid removed. They did a phenomenal job. Hurt like hell, but not for long. I heal very fast, too, which helps. Women’s College Hospital in Toronto offers these techniques. They should have some information on their website that can offer some insight yomammasayshi. Good luck and blessings for your mum.
Y’all will laugh, but horse paste took a cancer off my left temple. So help me God. Didn’t take long either.
Ivermectin and HCQ both seem to work well in cancer studies.
The temple? Surely, you jest!
I jest not! The left temple on my face!
That's awesome. Glad it worked out.
Did you rub it on the area or take it orally?
I’ve done both but this particular time, I used it topically. Husband and I had been doing horse paste prophylactically. I knew it was cancer but I had no intention of going to a doctor or hospital, no trust there anymore. Incidentally I was a nurse for over thirty years.
Give that 'bitch' some dog medication! And say hi to her.
Fenbendazole: https://www.nature.com/articles/s41598-018-30158-6
Joe Tippens' amazing experience with Fenbendazole https://www.youtube.com/watch?v=6a82Ra4c04Q
HCQ was added to chemo, for an increased rate of cure. Yuge jump in how much it helped. You can search NIH.gov for info on that.
There is an alternative to surgery, and the potential for follow-up plastic surgery. If your mom is especially concerned about surgery, and depending upon the actual location, Efudex is a possibility as well. But to imply that Efudex is "easier" is far from the truth. It causes the worst burn you can ever imagine, and the cancer cells are metabolized in such a way that they destroy themselves and eventually flake off. The whole process can take 6-8 weeks. But when you're done, the skin is like a baby's.
Efudex is most often prescribed when a face (or other part of the body) is covered with too many actinic keratoses to treat separately. There is a new formulation of the cream which adds vitamin D, and works more quickly and aids in the healing, too.
Many supplements, including almost every fruit and vegetable extract, fight cancer.
Curcumin, quercetin, resveratrol (which works well topically for melanoma; don't know how it would do for what your mom has), etc etc. A Supplement may be known for only ONE thing (e.g., cranberry fights urinary infections) but in almost all cases the supplement will have ADDITIONAL benefits including, typically, fighting cancer at one or more stages -- cranberry in fact has been shown in studies to fight cancer, for example. Poke around, you'll see what I mean. It's APPALLING how this has all been swept under the rug in favor of toxic chemical "therapies" and other harmful-if-sometimes-helpful approaches.
Don't forget immune-system boosters, especially if your mom has had (or will have) chemo, which greatly weakens the immune system, or has been jabbed, which is even worse. You NEED your immune system working well if you have cancer.
Were it me, I'd be taking a LOT of those things, starting with curcumin, which appears to be the apex predator when it comes to cancer. Hundreds, more likely THOUSANDS of studies supporting it. Be smart, do some research, watch the dosing, and so on, but there is good evidence that an intense regimen of carefully chosen supplements (plus good diet, some exercise, etc) will improve the odds against cancer and probably improve the quality of life as well.
I don't have time to dig out links right now but here's a good place to start: Life Extension's Protocol page. It's not the final word on things but a solid, curated place to start.
Best wishes to your mom for a swift and complete recovery. She's fortunate to have you looking out for her.
A natural product alternative is https://www.curaderm.net/
I’ve used it to treat facial basal and squamous cell carcinomas. It’s inexpensive and it works. The only downside is treatment times are somewhat unpredictable because it works to seek out and destroy the entire cancer, which is often like an iceberg where what’s visible at the surface is just a fraction of the whole lesion. Start to end treatment times will last from a few weeks to a few months depending on the size of the lesion.
The good news is it has no effect on normal cells, so unlike surgery it doesn’t involve removing good cells with the bad ones. The result is cosmetically superior to Mohs or other surgical methods and involves no risk of requiring plastic surgery to “clean up” after the cancer surgery. When finished it’s as if the cancer never existed and even your dermatologist will not notice the treated areas unless they really look hard.
There’s a support group for the product and its users on Facebook, which is the only time I’ve ever found a use for that service.
Depending on location this version of surgery may be more appropriate. Not always locally available.
https://www.skincancer.org/treatment-resources/mohs-surgery/
A good doctor or clinic skilled in Mohs procedure will be a great benefit. Only as invasive as the cancer itself. They remove the cancer carefully, taking only as much tissue as needed and testing for cancer presence or lack thereof before proceeding further. The skill of the doctor when it comes to reconstructive surgery is an important factor to consider. There are 3 types of skin cancer. Basal cell, which is very localized, squamous, which is local in nature but can spread to nearby tissue at a faster rate, and melanoma which can spread to other organs and be devastating.
I, personally have had 7 basal cell cancers and one melanoma removed. My sisters have had more than myself, of all three kinds. We were all children of the sun growing up in Texas in the early 60's. It is not a pleasant experience, but it is not horrible. The removal is far simpler than the reconstructive surgery. Early detection is key. A skilled reconstructive surgeon is worth their weight in gold.
I unknowingly let mine get worse, unaware what they were. My sister finally convinced me to seek help. The doctor has to remove the cancerous tissue as far as it leads. I was lucky. I had most of the bottom right quarter of my nose and a dime sized part of my left ear removed. I also had smaller ones on my upper lip and left eyelid removed. The reconstructive surgery was not pleasant, but I must admit was not terribly painful. All done with local anesthetics. Two months later, you would never know anything had ever even happened. The first two weeks I looked like somebody beat the crap out of me.
If you have a persistent sore or what appears to be a pimple or boil that just won't go away, get to a dermatologist. Sooner is better.
I don't know if it applies to this specific situation, but you might research the relationship between iodine deficiency and cancer.
https://pubmed.ncbi.nlm.nih.gov/21664718/
Supplement use and risk of cutaneous squamous cell carcinoma
Maryam M Asgari et al. J Am Acad Dermatol. 2011 Dec.
Background: Laboratory and epidemiologic studies suggest that certain dietary supplements may alter risk of cutaneous squamous cell carcinoma (SCC).
Objective:
We sought to examine the association between supplement use and SCC risk.
Methods:
Cases (n = 415) were defined as Kaiser Permanente Northern California members with a pathology-verified SCC in 2004 and control subjects (n = 415) were age-, sex-, and race-matched members with no history of skin cancer. Supplement use and SCC risk factors were ascertained by questionnaire. Associations of SCC with use of multivitamins; vitamins A, C, D, and E; and grape seed extract were estimated as odds ratios and 95% confidence intervals using conditional logistic regression. Models were adjusted for SCC risk factors and other supplement use.
Results:
Grape seed extract users had a significantly decreased risk of cutaneous SCC (adjusted odds ratio 0.26, confidence interval 0.08-0.89, P = .031). Multivitamin use was associated with a borderline significant reduction in SCC risk (adjusted odds ratio 0.71, confidence interval 0.51-1.00, P = .049). Use of vitamins A, C, D, and E was not associated with SCC risk.
Limitations:
The data may be prone to recall and selection bias because of the case-control design. No information was obtained on dose or duration of supplement use.
Conclusions:
Use of grape seed extract may be associated with a decreased risk of cutaneous SCC. The other supplements included in our study did not reveal clear associations with SCC risk.
—
https://pubmed.ncbi.nlm.nih.gov/21612892/
Solanum incanum extract (SR-T100) induces human cutaneous squamous cell carcinoma apoptosis through modulating tumor necrosis factor receptor signaling pathway
Chin-Han Wu et al. J Dermatol Sci. 2011 Aug.
Background:
The Solanum species herbs have been used to treat cancer for centuries; however, the underlying mechanisms and effectiveness in vivo remain unclear.
Objectives:
SR-T100, extracted from the Solanum incanum, contains solamargine alkaloid as the main active ingredient. Here, we investigated the apoptosis-inducing effects of SR-T100 for targeting squamous cell carcinoma (SCC) in vitro and in vivo.
Methods:
We elucidated the mechanism by which SR-T100 induces apoptosis of human SCCs (A431, SCC4, SCC9, and SCC25) cells. The efficacy and safety issues were addressed regarding topical treatment of SR-T100 on UVB-induced cutaneous SCC of hairless mice and actinic keratoses (AKs) of human.
Results:
SR-T100 induces apoptosis in human SCCs cell lines by up-regulating the expressions of tumor necrosis factor receptors (TNFRs) and Fas, and downstream adaptors FADD/TRADD of the TNF-α and Fas ligand signaling cascades. SR-T100 also triggered the mitochondrial apoptotic pathway, as up-regulated cytochrome c and Bax, down-regulated Bcl-X(L). Animal experiments showed that all papillomas (35/35) and 27 of 30 UVB-induced microinvasive SCCs in hairless mice disappeared within 10 weeks after once-daily application of topical SR-T100. Furthermore, 13 patients, who suffered with 14 AKs, were treated with once-daily topical SR-T100 gel and 10 AKs cured after 16 weeks, showing negligible discomforts.
Conclusion:
Our studies indicate that SR-T100 induces apoptosis of SCC cells via death receptors and the mitochondrial death pathway. The high efficacy of SR-T100 in our preclinical trial suggests that SR-T100 is a highly promising herb for AKs and related disorders.
—
https://pubmed.ncbi.nlm.nih.gov/22705325/
Anti-skin cancer properties of phenolic-rich extract from the pericarp of mangosteen (Garcinia mangostana Linn.)
Jing J Wang et al. Food Chem Toxicol. 2012 Sep.
Skin cancers are often resistant to conventional chemotherapy. This study examined the anti-skin cancer properties of crude ethanol extract of mangosteen pericarp (MPEE) on human squamous cell carcinoma A-431 and melanoma SK-MEL-28 lines. Significant dose-dependent reduction in% viability was observed for these cell lines, with less effect on human normal skin fibroblast CCD-1064Sk and keratinocyte HaCaT cell lines. Cell distribution in G(1) phase (93%) significantly increased after 10 μg/ml of MPEE versus untreated SK-MEL-28 cells (78%), which was associated with enhanced p21(WAF1) mRNA levels. In A-431 cells, 10 μg/ml MPEE significantly increased the sub G(1) peak (15%) with concomitant decrease in G(1) phase over untreated cells (2%). In A-431 cells, 10 μg/ml MPEE induced an 18% increase in early apoptosis versus untreated cells (2%). This was via caspase activation (15-, 3- and 4-fold increased caspse-3/7, 8, and 9 activities), and disruption of mitochondrial pathways (6-fold decreased mitochondrial membrane potential versus untreated cells). Real-time PCR revealed increased Bax/Bcl-2 ratio and cytochrome c release, and decreased Akt1. Apoptosis was significantly increased after MPEE treatment of SK-MEL-28 cells. Hence, MPEE showed strong anti-skin cancer effect on these two skin cancer cell lines, with potential as an anti-skin cancer agent.
—
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562900/
Grape seed proanthocyanidines and skin cancer prevention: Inhibition of oxidative stress and protection of immune system Santosh K. Katiyar Abstract Overexposure of the skin to ultraviolet (UV) radiation has a variety of adverse effects on human health, including the development of skin cancers. There is a need to develop nutrition-based efficient chemopreventive strategies. The proanthocyanidins present in grape seeds (Vitis vinifera) have been shown to have some biological effects, including prevention of photocarcinogenesis. The present communication discusses the in vitro and in vivo studies of the possible protective effect of grape seed proanthocyanidins (GSPs) and the molecular mechanism for these effects. In SKH-1 hairless mice, dietary supplementation with GSPs is associated with a decrease of UVB-induced skin tumor development in terms of tumor incidence, tumor multiplicity, and a decrease in the malignant transformation of papillomas to carcinomas. It is suggested that the chemopreventive effects of dietary GSPs are mediated through the attenuation of UV-induced: (a) oxidative stress; (b) activation of mitogen-activated protein kinases and nuclear factor-κB signaling pathways; and (c) immunosuppression through alterations in immunoregulatory cytokines. Collectively, these studies indicate protective potential of GSPs against experimental photocarcinogenesis in SKH-1 hairless mice, and the possible mechanisms of action of GSPs, and suggest that dietary GSPs could be useful in the attenuation of the adverse UV-induced health effects in human skin.
—
https://pubmed.ncbi.nlm.nih.gov/8620443/
Chemoprevention of lung and skin cancer by Beta vulgaris (beet) root extract
G J Kapadia et al. Cancer Lett. 1996.
Abstract
The in vitro inhibitory effect of Beta vulgaris (beet) root extract on Epstein-Barr virus early antigen (EBV-EA) induction using Raji cells revealed a high order of activity compared to capsanthin, cranberry, red onion skin and short and long red bell peppers. An in vivo anti-tumor promoting activity evaluation against the mice skin and lung bioassays also revealed a significant tumor inhibitory effect. The combined findings suggest that beetroot ingestion can be one of the useful means to prevent cancer.
—
https://pubmed.ncbi.nlm.nih.gov/19776181/
Olive leaf extract and its main component oleuropein prevent chronic ultraviolet B radiation-induced skin damage and carcinogenesis in hairless mice
Yoshiyuki Kimura et al. J Nutr. 2009 Nov.
Chronic exposure to solar UV radiation damages skin, increasing its thickness and reducing its elasticity, and causes skin cancer. Our aim in this study was to examine the effects of an olive leaf extract and its component oleuropein on skin damage and the incidence of skin tumors caused by long-term UVB irradiation in hairless mice. Male hairless mice (5 wk old) were divided into 6 groups, including a non-UVB group, a vehicle-treated UVB group (control), 2 olive leaf extract-treated UVB groups, and 2 oleuropein-treated UVB groups. Five groups were UVB irradiated (36-180 mJ/cm(2)) 3 times each week for 30 wk and skin thickness and elasticity after UVB irradiation were measured every week. Olive leaf extract (300 and 1000 mg/kg) and oleuropein (10 and 25 mg/kg) were administered orally twice daily every day for 30 wk. The extract and oleuropein significantly inhibited increases in skin thickness and reductions in skin elasticity, and skin carcinogenesis and tumor growth.(cont.)
—
https://pubmed.ncbi.nlm.nih.gov/24325618/
Molecular mechanism of apoptosis induction in skin cancer cells by the centipedegrass extract
2013 Srilatha Badaboina et al. BMC Complement Altern Med.
Background: Centipedegrass extract (CGE) is mainly composed of maysin and its derivatives, which are recognized internationally as natural compounds. Compared to other flavonoids, maysin has a unique structure in that mannose is bound to the flavonoid backbone. CGE exhibits some biological properties in that it can function as an anti-oxidant, anti-inflammatory, anti-adipogenic, and insecticidal. Whether CGE has other biological functions, such as anti-cancer activity, is unknown.
Methods: B16F1 (mouse) and SKMEL-5 (human) cells were treated with CGE, and their subsequent survival was determined using MTT assay. We performed a cell cycle analysis using propidium iodide (PI), and detected apoptosis using double staining with annexin V-FITC/PI. In addition, we examined mitochondrial membrane potentials using flow cytometry, as well as signaling mechanisms with an immunoblotting analysis.
Results: CGE inhibited skin cancer cell growth by arresting the cell cycle in the G2/M phase, and increased both early and late apoptotic cell populations without affecting normal cells. Furthermore, we observed mitochondrial transmembrane depolarization, increased cytochrome-c release, caspase-3 and caspase-7 activation, and increased poly ADP-ribose polymerase degradation. CGE also downregulated activation of p-AKT, p-glycogen synthase kinase-3β (GSK-3β), and p-BAD in a time-dependent manner. LY294002 inhibition of phosphoinositide 3-kinase (PI3K) significantly sensitized skin cancer cells, which led to an increase in CGE-induced apoptosis.
Conclusions: CGE controlled skin cancer cell growth by inhibiting the PI3K/AKT/GSK-3β signaling pathway and activating the effector caspases. This study is the first to demonstrate anti-cancer properties for CGE, and that CGE may be an effective therapeutic agent for treating skin cancer.
—
https://pubmed.ncbi.nlm.nih.gov/23394841/
Durable response of cutaneous squamous cell carcinoma following high-dose peri-lesional injections of Viscum album extracts--a case report
2013 Case Reports
Paul Georg Werthmann et al. Phytomedicine.
Background:
Cutaneous squamous cell carcinoma (CSCC) is a common locally invasive skin cancer which rarely metastasises. First-line treatment is surgical excision, which is curative in most cases. Viscum album extract (VAE) is a widely used herbal cancer treatment with cytotoxic, apoptogenic and immunological effects, but has not been investigated in CSCC.
Case presentation:
A 78-year-old patient with histologically diagnosed CSCC refused surgical excision and was treated with peri-lesional high-dose VAE. After 10 months of treatment the CSCC had disappeared clinically. The patient has been recurrence-free for 4 years.
Conclusion:
The presented case shows clinical response of a CSCC to high-dose peri-lesional VAE injections. Further research on VAE in CSCC is warranted.
Cutting often results in disfiguration [I have known a couple of people who had skin cancer and their "after" results were terrible] and it still returns-- maybe get a second opinion from an alternative/holistic practitioner including diet changes, juicing greens and fruit, baking soda, raw apple cider vinegar, apricot seeds, someone even used prid, there are a number of possibilities. I myself have fair skin and had damaged areas and scars on my face and chest, and after a few years of eating mostly raw organic fruits greens and veggies my skin is now soft and pretty good for 60+.
Look to see if there is a MOHS surgeon around. This would be the best way to remove the cancer. I am not a medical person, but I am familiar with this problem.
Hey Yomammasayshi - Question for you - have the docs tried cryotherapy with liquid nitrogen on the cancerous spot? I am a stage III survivor and whenever I get any kind of raised or textured spot, freckle or lump on my skin anywhere since my diagnosis four years ago, I simply buy a canister or two of Dr. Scholl's Freeze Away liquid nitrogen and freeze the spot until I am sure it has been fully frozen (as little as 20 seconds to 1 minute). Soon the spot swells and blisters and scabs and heals and about two weeks later, the thing is GONE.
If I keep the spot out of the sun during healing there is no scar at all. It's fantastic. Freezing it will kill it down to its roots and no trauma or disfigurement will result to the area, unlike if she has a big divot cut out by the doc. Surgeons live to 'cut'. They'll take a nice big gouge of flesh and leave a big wound in her body in order to justify their expensive education. Freezing is by far the better solution.
If by chance any of the cancer appears to still be detectable after the first freeze, you simply hit it again. I had a thick painful lump in my calf that I had to freeze about 6 times over the course of a week, and that did the trick. A small freckle-sized spot usually is killed on the first attempt.
The Dr. Scholl's product is identical process to what the dermatologists use in their practice. If she can reach it herself it is easy to do yourself. If not, employ a sensitive family member to do it for her in the comfort of her own home.
I am available for questions if she has any.
Here's an article on the subject:
Treating Squamous Cell Carcinoma - American Cancer
Societyhttps://www.cancer.org › cancer › squamousl-cell-carcino...
Cryotherapy (Or cryosurgery) is used for some early squamous cell cancers, especially in people who can't have surgery, but is not recommended for larger invasive tumors or those on certain parts of the nose, ears, eyelids, scalp, or legs.
Jun 24, 2020
I had squamous cell carcinoma on the inside of my cheek. Before the Chy-an virus, my doctor prescribed HCQ after a quick laser surgery. In total remission now.
Get the surgery. I had one on my hand and had it taken off. It was deep and left a about three inch scar because I let it get so large the surgeon had to put a lot of skin to close the gap, and that meant a lot longer scar.
The scar has faded to the point it isn't very noticeable. With a scar on her face they might be able to do some cometic surgery to hide it. It will depend on the size of the cancer how intrusive they have to be.
Wow, so much good information here. I will add my anecdotal experience. About 10 years ago, I got what looked like a small skin cancer on my arm. I immediately began taking grape seed extract and turmeric (watch the dosage, they are both blood thinners) and ate only vegetables. Wish I had known about ivermectin, but I made a poultice of coconut oil, baking soda, and salt and applied that 3x a day. As the spot shrank, I began to be a little more aggressive and scrubbed it daily with the poultice. (I would be hesitant to scrub in the facial area). In six weeks, it was completely gone and I was left with a smooth white spot. Some time later, my husband developed a spot that looked exactly like the one I had and his was confirmed to be SCC. If another pops up, however, I will definitely check into the curaderm.
Quercitin. Latest greatest. Hope I spelled it correctly.
Generally sun on face causes basal cell carcinomas. Squamous cell is usually on the lower lip. I assume an incisional biopsy was done if you are reporting it as squamous cell. Those are more aggressive and widely excised. Don't fool around and follow the advice of the surgeon after the pathology report is received.
Rick Simpson method cannabis oil watch his videos, very simple to make, use topically can also try coconut oil soaked in cannabis. my friend used black slave (Balck Slave is Indian blood root and a caustic powder) on his skin cancer for many years, Arms, face and ears, it would turn into a open wound and pop out a hard white looking glob, then he had to heal the wound, He switched to the Cannabis oil, it just vanished in a few days to a week using rick Simpson cannabis oil homemade. The Simpson oil is cannabis soaked in alcohol then cook off the alcohol, what remains is a black tar oil. I know a fella that makes it as well he has a website, he uses grape seed oil infused cannabis soaked for two to three months. topically or ingested. not heated so most folks that eat it do not get high. you can also just soak cannabis oil in Coconut oil. Coconut oil is non inflammatory wile grape seed oil is inflammatory. it does work for most people, we used to make gobs and give irt away. I have a friend that soaked his cannabis in Everclear 190 proof and uses it topically for all kinds of pain issues, he's given over 300 roll-on bottles away.
There was a lady on here that used ivermectin horse paste for her mother topically as well but it wasn't skin cancer... she posted her mother's blood work to prove it. I do not recall the type of cancer she had though. Good Luck Pray Hard.
This is called the MOHS technique. I had it done when I had eye cancer, and had to have part of my eyelid removed. They did a phenomenal job. Hurt like hell, but not for long. I heal very fast, too, which helps. Women’s College Hospital in Toronto offers these techniques. They should have some information on their website that can offer some insight yomammasayshi. Good luck and blessings for your mum.