(1) Quinine is not hydroxychloroquine. (2) Quinine has been in use as a bark extract to treat malaria since 1632. (3) Quinine was chemically isolated in 1820.
But hydroxychloroquine has been known to be safe since 1955.
It is based on Chloroquine which is a synthetic drug that happens to share the same mechanism of action as Quinine. So completely different but effects the body in a similar/same way.
HCQ is chloroquine with an added hydroxyl group. Chloroquine is a modification of quinine that terminates one part of the molecule with a chlorine atom. No sulfur anywhere in the formulas for any of these. The modifications were mainly to suppress the side effects.
Quinine was extracted from the bark of a particular plant. It may have been isolated later as a particular component (before establishing that it was chemically distinct).
Quinine water was often used in the tropics, which gave rise to the gin-and-tonic, as a way of moderating the bitter taste.
Gin is not added due to the taste, but because Gin is made from junipers which has its own healing properties against viruses, parasites and bacteria - Gin and Quinine are a good combination.
Tonic is the bitter part with the quinine (from lemon, grapefruit or something else).
Together it was the right combination against malaria symptoms.
It’s one of the first drugs I learned about in nursing school. It played a huge role in waking me up when all of a sudden it became deadly. I read about the new study and found 4x the normal high dose was used in the study. The study intentionally overdosed the participants. It was my red pill.
They are chemical derivatives of one another. Pointing to a bottle of quinine from over a century ago does not prove anything about hydroxychloroquine. I'm just trying to point out the relevant facts.
Water and hydrogen peroxide are "related," but we have known water since the beginning of time whereas hydrogen peroxide was discovered in 1818; the former is essential to health and the latter is poisonous. Slight differences in the chemical formula can lead to huge differences in properties.
You mean it wasn't all snake oil? Because this would have been real medicine! Now, let's not assume that it was manufactured perfectly, mind you. Back in the day, chemistry was a real "throw everything at the wall and see what sticks" type of deal.
Ancient Apocalypse trending on Netflix, awakening millions who've watched and finally started questioning the bullshit evolutionist narrative of apes to humans, "our ancestors were cavemen" idiots. Coincidentally, watching that series prompted me to rewatch the most recent Indiana Jones... Kingdom of the Crystal Skull. Came out 2008. Saw in theaters. Thought it was dumb then. But I get it now.
And even without the deep understanding of the 'whys', they knew the scientific method well enough. Do something, then see what happens. If it works, keep doing it. If it doesn't work, do something else.
Which is a hell of a lot better than today's "science" of: if it doesn't work, do it twice as much.
And they didn't have FDA requirements of 5 yr assessment trials (longer for pregnant) nor the most powerful lobbyists in D.C. shilling for pharmaceutical giants to figure out medicinal dosages & such are just weak enough to never cure, only treat. (save govt authorized emergency gene replacement therapies)
They have chemical similarities, but similar chemicals can have very different effects- for example, chlorophyll and hemoglobin, or estradiol and testosterone, or serotonin and DMT, or ethanol and methanol.
While I’m not going to mention things that get peoples hackles up, you would have to wonder when you look at art, like paintings, music, books, etc., in the 1700-1800s, it’s far superior than anything we can reproduce today. Many techniques have been lost. And they didn’t have the tools we have today, but made instruments that even have scientists scratching their heads.
Good info. That's just the beginning too. At the same time pharma (or its infancy foot soldiers) was giving mercury sublimate and other detrimental concoctions, herbal medicine was thriving among the common people. Publicity (media) alone is the reason we ended up with the shit show we currently have. The pharma industry conspired to blacklist the growing herbal industry with the support of the courts of the day. It gets so much worse.
'Green Pharmacy' by Barbara Griggs is an excellent history of medicine and the old battle between the parties.
(1) Quinine is not hydroxychloroquine. (2) Quinine has been in use as a bark extract to treat malaria since 1632. (3) Quinine was chemically isolated in 1820.
But hydroxychloroquine has been known to be safe since 1955.
I believe HCQ is just the sulfated version, made solid and more stable, longer shelf life, etc.
Since 1632?? Wow, I didn't know it went that far back
It is based on Chloroquine which is a synthetic drug that happens to share the same mechanism of action as Quinine. So completely different but effects the body in a similar/same way.
HCQ is chloroquine with an added hydroxyl group. Chloroquine is a modification of quinine that terminates one part of the molecule with a chlorine atom. No sulfur anywhere in the formulas for any of these. The modifications were mainly to suppress the side effects.
Quinine was extracted from the bark of a particular plant. It may have been isolated later as a particular component (before establishing that it was chemically distinct).
Quinine water was often used in the tropics, which gave rise to the gin-and-tonic, as a way of moderating the bitter taste.
Gin is not added due to the taste, but because Gin is made from junipers which has its own healing properties against viruses, parasites and bacteria - Gin and Quinine are a good combination.
Tonic is the bitter part with the quinine (from lemon, grapefruit or something else).
Together it was the right combination against malaria symptoms.
It’s one of the first drugs I learned about in nursing school. It played a huge role in waking me up when all of a sudden it became deadly. I read about the new study and found 4x the normal high dose was used in the study. The study intentionally overdosed the participants. It was my red pill.
They are related
They are chemical derivatives of one another. Pointing to a bottle of quinine from over a century ago does not prove anything about hydroxychloroquine. I'm just trying to point out the relevant facts.
Water and hydrogen peroxide are "related," but we have known water since the beginning of time whereas hydrogen peroxide was discovered in 1818; the former is essential to health and the latter is poisonous. Slight differences in the chemical formula can lead to huge differences in properties.
It’s probably in the medical research museum at Lilly HQ in Indy. I’ll have confirmation shortly.
I reversed searched it on TinEye and found nothing, just FYI.
Found in a museum in Texas according to this tweet ...
https://mobile.twitter.com/DavidG02986909/status/1407108418423361540
Found while digging - Will someone archive it?
Go to page 236 (272) for diseases/remedies!
Eli Lilly - Handbook of Pharmacy and Therapeutics, 1919:
http://www.survivorlibrary.com/library/hand_book_of_pharmacy_and_therapeutics_1919.pdf
A whole library of old books "not for survival, but for survivors":
http://www.survivorlibrary.com/10-static/174-role-of-the-library.html
http://www.survivorlibrary.com/library-download.html
TinEye will only look for this picture, nothing else about the picture.
You mean it wasn't all snake oil? Because this would have been real medicine! Now, let's not assume that it was manufactured perfectly, mind you. Back in the day, chemistry was a real "throw everything at the wall and see what sticks" type of deal.
"Back in the day" there were a lot of skilled alchemists who developped their craft into the pharmaceutical, medical and chemical field.
Oldest pharmacy in Germany in Trier "The Golden Lion" pharmacy from 1241.
https://sedulia.blogs.com/photos/europe_today/trier_oldest_pharmacy_in_germany_1241.html
https://en.wikipedia.org/wiki/History_of_pharmacy
Yup.
The idea our ancestors were stupid always cracks me up.
Most today couldn't stand toe to toe academically.
Ancient Apocalypse trending on Netflix, awakening millions who've watched and finally started questioning the bullshit evolutionist narrative of apes to humans, "our ancestors were cavemen" idiots. Coincidentally, watching that series prompted me to rewatch the most recent Indiana Jones... Kingdom of the Crystal Skull. Came out 2008. Saw in theaters. Thought it was dumb then. But I get it now.
And even without the deep understanding of the 'whys', they knew the scientific method well enough. Do something, then see what happens. If it works, keep doing it. If it doesn't work, do something else.
Which is a hell of a lot better than today's "science" of: if it doesn't work, do it twice as much.
Since 1832 we had a weights and measurements in the U.S.
Not exactly throw and wall stick.
And they didn't have FDA requirements of 5 yr assessment trials (longer for pregnant) nor the most powerful lobbyists in D.C. shilling for pharmaceutical giants to figure out medicinal dosages & such are just weak enough to never cure, only treat. (save govt authorized emergency gene replacement therapies)
Quinne and Gin is what the Slave Masters drank in India.
Hydroxychloroquine: C18H26ClN3O
Quinine Valerate: C25H34N2O4
They both have the same quinoline double ring but they're definitely not the same substance.
I am 100% asking this sincerely, but, while you are right, my dumb brain thinks:
Hydroxychloriquine = Quinine, just in a different form. I know I'm technically wrong, but, in terms of the efficacy of the substance, am I correct?
Thanks for sharing your smarts with us.
They have chemical similarities, but similar chemicals can have very different effects- for example, chlorophyll and hemoglobin, or estradiol and testosterone, or serotonin and DMT, or ethanol and methanol.
While I’m not going to mention things that get peoples hackles up, you would have to wonder when you look at art, like paintings, music, books, etc., in the 1700-1800s, it’s far superior than anything we can reproduce today. Many techniques have been lost. And they didn’t have the tools we have today, but made instruments that even have scientists scratching their heads.
To be fair we also used to think that leeches were bemeficial
It would be cooler if it was a vintage bottle of Coke. The good kind.
Good info. That's just the beginning too. At the same time pharma (or its infancy foot soldiers) was giving mercury sublimate and other detrimental concoctions, herbal medicine was thriving among the common people. Publicity (media) alone is the reason we ended up with the shit show we currently have. The pharma industry conspired to blacklist the growing herbal industry with the support of the courts of the day. It gets so much worse. 'Green Pharmacy' by Barbara Griggs is an excellent history of medicine and the old battle between the parties.