There are anano particles in anything the says "natural flavor"

I agree, that is an apt comparison. Here is some similarities if found between the two.

Clinical Similarities Between Cancer and Alzheimer’s Disease

1. Protein Misfolding and Aggregation:

   • Both conditions involve the misfolding and aggregation of proteins that disrupt normal cellular functions.
     • Alzheimer’s Disease: Amyloid-beta plaques and tau tangles.
     • Cancer: Misfolded proteins affecting cell signaling pathways.

2. Dysregulated Pathways:

   • Dysregulation of critical cellular pathways is a hallmark of both diseases.
     • Alzheimer’s Disease: Pathways related to cellular homeostasis, neuroinflammation, and synaptic function.
     • Cancer: Pathways controlling cell proliferation, apoptosis, and DNA repair.

3. Genetic Mutations:

   • Genetic mutations play a significant role in disease onset and progression.
     • Alzheimer’s Disease: Mutations in APP, PSEN1, PSEN2 genes, and risk genes like APOE4.
     • Cancer: Mutations in oncogenes, tumor suppressor genes, and DNA repair genes.

4. Chronic Inflammation:

   • Chronic inflammation is a common feature, contributing to disease progression.
     • Alzheimer’s Disease: Neuroinflammation with activated microglia and astrocytes.
     • Cancer: Inflammatory cells in the tumor microenvironment.

5. Oxidative Stress:

   • Oxidative stress is implicated in cellular damage in both diseases.
     • Alzheimer’s Disease: Leads to neuronal damage and death.
     • Cancer: Causes DNA damage, promoting mutations and cancer progression.

6. Cellular Senescence:

   • Accumulation of senescent cells affects disease progression.
     • Alzheimer’s Disease: Senescent cells contribute to neurodegeneration.
     • Cancer: Senescent cells promote the tumor microenvironment but also act as a tumor-suppressing mechanism.

7. Epigenetic Changes:

   • Epigenetic modifications influence disease development.
     • Alzheimer’s Disease: DNA methylation and histone modification.
     • Cancer: Activation of oncogenes or silencing of tumor suppressor genes.

8. Cell Cycle and Apoptosis:

   • Abnormal regulation of cell cycle and apoptosis pathways.
     • Alzheimer’s Disease: Contributes to neuronal death.
     • Cancer: Leads to uncontrolled cell proliferation and resistance to apoptosis.

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Shared phytochemicals that modulate progression

Curcumin

• Cancer: Curcumin, found in turmeric, has been shown to have anti-inflammatory, antioxidant, and anticancer properties. It can inhibit the growth of cancer cells, induce apoptosis (programmed cell death), and inhibit angiogenesis (formation of new blood vessels that feed tumors).
• Alzheimer’s: Curcumin has neuroprotective properties, including reducing amyloid plaque accumulation, inhibiting tau protein aggregation, and reducing oxidative stress and inflammation in the brain.

Resveratrol

• Cancer: Resveratrol, found in grapes, berries, and peanuts, exhibits anticancer properties by inhibiting cell proliferation, inducing apoptosis, and modulating various signaling pathways involved in cancer progression.
• Alzheimer’s: Resveratrol has neuroprotective effects, including reducing beta-amyloid plaque formation, protecting against oxidative stress, and improving mitochondrial function.

Epigallocatechin Gallate (EGCG)

• Cancer: EGCG, a catechin found in green tea, has strong antioxidant properties and can inhibit cancer cell growth, induce apoptosis, and modulate signaling pathways involved in cancer development.
• Alzheimer’s: EGCG can reduce the formation of beta-amyloid plaques, protect neurons from oxidative damage, and improve cognitive function.

Quercetin

• Cancer: Quercetin, found in onions, apples, and berries, has been shown to inhibit cancer cell proliferation, induce apoptosis, and inhibit angiogenesis. It also has anti-inflammatory and antioxidant properties.
• Alzheimer’s: Quercetin has neuroprotective effects, including reducing oxidative stress, inhibiting beta-amyloid aggregation, and protecting neurons from toxicity.

Sulforaphane

• Cancer: Sulforaphane, found in cruciferous vegetables like broccoli, has potent anticancer effects. It can inhibit cancer cell growth, induce phase II detoxification enzymes, and promote apoptosis.
• Alzheimer’s: Sulforaphane has been shown to reduce oxidative stress, inhibit the formation of beta-amyloid plaques, and protect against neuronal damage.

Luteolin

• Cancer: Luteolin, found in celery, parsley, and various herbs, exhibits anticancer properties by inhibiting cell proliferation, inducing apoptosis, and inhibiting angiogenesis. It also has anti-inflammatory and antioxidant effects.
• Alzheimer’s: Luteolin can reduce neuroinflammation, inhibit beta-amyloid formation, and protect against oxidative stress, contributing to its neuroprotective effects.

Not impersonating. It's a completely different. Pick two:

• indistinguishably realistic (not simply life like but truly passable)
• flexible (down to fine wrinkles)
• a recognizable famous or known person. (Matching all wrinkle patters and fine wrinkles)

Conservative people tend to do well financially thus making an easy life for their kids, who then grow up where everything comes easy and become entitled liberals

Not entirely, but yes aluminum does contribute. It's more of a "perfect storm" scenario where a few things together end up causing it. Aluminum causes inflammation, blocks tryptophan, and Alters gut microbiota, causing chelation and it then enters the blood brain barrier.

While I agree that the cells are immoral, I don't think the cells themselves cause autism. It's much more likely that autism is caused by the vaccines through an inflammatory response which cascades into a change in the gut microbiom which then creates a systemic signaling change. If you take a look at my history you may see I enjoy researching. If you would like i can send you some clinical data on it. One quick data point I find interesting is that a study was done in which gut bacteria from an autistic human was injected into mice, the mice then exhibited autistic-like behavior.

Exactly!

correct but the very same phytochemicals help with that as well!

Pathway of Tau Hyperphosphorylation

• 1. Normal Tau Function Tau protein normally binds to and stabilizes microtubules, essential for neuronal structure and intracellular transport.

• 2. Kinase Activation Glycogen Synthase Kinase 3 Beta (GSK-3β)

• Activation: GSK-3β is activated through insulin signaling dysregulation, Wnt signaling, and inflammatory cytokines.

• Phytochemical Modulation:

  • Curcumin: Inhibits GSK-3β activity, reduces tau phosphorylation.
  • Resveratrol: Activates AMPK and sirtuins, inhibiting GSK-3β.
  • Epigallocatechin Gallate (EGCG): Directly inhibits GSK-3β.

Cyclin-Dependent Kinase 5 (CDK5)

• Activation: CDK5 is activated by p35 and, in pathological conditions, by p25 (cleaved from p35).
• Phytochemical Modulation:
  • Curcumin: Reduces CDK5 activity and the conversion of p35 to p25.
  • Quercetin: Inhibits CDK5 activity.

3. Phosphatase Inhibition Protein Phosphatase 2A (PP2A)

• Function: PP2A dephosphorylates tau, maintaining its normal state.
• Inhibition: Oxidative stress, altered methylation, and inhibitory proteins reduce PP2A activity.
• Phytochemical Modulation:
  • Hesperidin: Increases PP2A activity.
  • Luteolin: Protects PP2A from oxidative stress-induced inhibition.
  • Resveratrol: Enhances PP2A activity by modulating its methylation state.

Resulting Hyperphosphorylation Cumulative Effect: Increased kinase activity (GSK-3β and CDK5) and decreased phosphatase activity (PP2A) lead to excessive tau hyperphosphorylation.

• Impact on Tau: Hyperphosphorylated tau detaches from microtubules, causing microtubule destabilization and disrupted intracellular transport.
• Phytochemical Modulation:
  • Curcumin, Resveratrol, EGCG, Quercetin, Luteolin, Hesperidin: These phytochemicals inhibit kinases, activate phosphatases, and reduce oxidative stress, mitigating tau hyperphosphorylation and its detrimental effects on neurons.

Mechanistic Insights and Phytochemical Modulation

GSK-3β Activation

• Pathways: Dysregulated insulin signaling and pro-inflammatory cytokines (e.g., TNF-α, IL-1β) activate GSK-3β.
• Phytochemical Modulation:
  • Curcumin, Resveratrol, EGCG: Anti-inflammatory properties reduce cytokine levels and inhibit GSK-3β.

CDK5 Activation

• p35 to p25 Conversion: Pathological conditions convert p35 to p25, forming a hyperactive CDK5/p25 complex.
• Neurotoxicity: The CDK5/p25 complex phosphorylates tau and contributes to neurotoxicity.
• Phytochemical Modulation:
  • Curcumin, Quercetin: Inhibit the p35 to p25 conversion, reducing CDK5 activity.

PP2A Inhibition

• Oxidative Stress: Impairs PP2A by oxidizing its catalytic subunit.
• Methylation: Altered methylation reduces PP2A activity.
• Inhibitory Proteins: Upregulated in Alzheimer’s, further inhibiting PP2A.
• Phytochemical Modulation:
  • Hesperidin, Luteolin: Reduce oxidative stress and protect PP2A.
  • Resveratrol: Enhances PP2A activity through methylation modulation.

No prob! But I'm not the op lol

Hard to dell from that distance if it's him or not. Doesn't really.move like him.

Surah Al-Imran (3:42): "And (mention) when the angels said, 'O Mary, indeed Allah gives you good tidings of a word from Him, [Jesus] the Messiah, the son of Mary—distinguished in this world and the Hereafter and those who are near to Allah.'"

This verse highlights Mary's special status and the divine message she received. Additionally, in Surah Maryam (19:16-26), her story is elaborated, affirming her purity and the miraculous birth of Jesus (Isa):

Surah Maryam (19:16-26):

• In these verses, the Quran describes Mary’s dedication and the miraculous birth of Jesus, emphasizing her virtue and the divine favor bestowed upon her.

• TLDR Reelin is a glycoprotein crucial for brain development and function, influencing neuronal migration, synaptic plasticity, and cognitive processes. Understanding the pathways regulating Reelin and the effects of various phytochemicals on its expression can offer insights into potential therapeutic strategies for cognitive decline and neurodegenerative diseases. However, given the PI3K-Akt pathway’s role in both brain health and cancer, careful consideration is necessary when targeting Reelin upregulation, especially in cancer patients.

Role of Reelin in the Brain

• Neuronal Migration and Positioning: During brain development, Reelin is essential for proper neuronal layering in the cortex and hippocampus.
• Synaptic Plasticity and Function: In the adult brain, Reelin promotes synaptic plasticity, crucial for learning and memory.
• Cognitive Health: Adequate Reelin levels are associated with cognitive resilience, while reduced Reelin is linked to cognitive decline and neurodegenerative diseases like Alzheimer's.

Routes of Reelin Activation

1. Neuronal Activity

   • Synaptic Activity: Enhanced synaptic activity and neuronal firing increase Reelin expression.
   • Neurotransmitter Release: Glutamate acting on NMDA receptors promotes Reelin production.

2. Neurotransmitters and Neurotrophic Factors

   • Glutamate: NMDA receptor activation by glutamate increases Reelin.
   • BDNF (Brain-Derived Neurotrophic Factor): TrkB receptor activation by BDNF upregulates Reelin.

3. Transcriptional and Epigenetic Regulation

   • Transcription Factors: CREB activation increases RELN gene transcription.
   • Epigenetic Modifications: Histone acetylation and reduced DNA methylation at the RELN promoter enhance its expression.

4. Environmental and Lifestyle Factors

   • Physical Exercise: Promotes neurogenesis and synaptic plasticity, increasing Reelin levels.
   • Cognitive Stimulation: Learning and complex tasks enhance Reelin expression.

5. Dietary and Nutritional Factors

   • Omega-3 Fatty Acids: These support Reelin expression.

------‐----‐----------------

Phytochemicals Upregulating Reelin

1. Curcumin

   • Mechanism: Antioxidant and anti-inflammatory effects, modulation of CREB and BDNF pathways.

2. Resveratrol

   • Mechanism: Activation of sirtuins, reduction of oxidative stress and inflammation.

3. Epigallocatechin Gallate (EGCG)

   • Mechanism: Antioxidant properties, modulation of PI3K-Akt pathway.

4. Quercetin

   • Mechanism: Antioxidant and anti-inflammatory effects, modulation of neuroprotective pathways.

5. Pterostilbene

   • Mechanism: Similar to resveratrol, neuroprotective through antioxidant and anti-inflammatory actions.

6. Luteolin

   • Mechanism: Anti-inflammatory and antioxidant properties, enhancement of Reelin expression.

7. Hesperidin

   • Mechanism: Neuroprotective effects through anti-inflammatory and antioxidant actions.

Potential Risks of Reelin Upregulation

• PI3K-Akt Pathway Activation: While beneficial for neuronal survival and plasticity, activation of this pathway can contribute to tumor growth and survival in cancer.
• Cancer Considerations: Upregulating Reelin might exacerbate cancer by enhancing the PI3K-Akt pathway. However, many phytochemicals that upregulate Reelin also exhibit anti-cancer properties so perhaps it's not entirely that important.

I'm on it, I will report back with my findings.

Yes

Yes, they also believe that Mary was the most blessed mother and most beloved by God.

It's basically the original Mormons. They make up their own book and own prophet, then hate on Paul.

It's always been the same biden, what matters is his handlers. And it's been clear this entire time he is a puppet. Real question is: for whom. The whole mask crap is a distraction.

And they claim to regulate it, then oops our product got out and is cross breeding with all the other foods of the same type oops

Thank you very much. I appreciate that. I hope you heal.if you have other question you are always welcome to shoot them my way.

The assailant is the only one at fault. The method the victims and victims family cope is of noones fault but the perpetrator.

Correct, this is a low quality post.

Just in case this isn't clear, they mean white compared to all other races combined.

I mean that's kina accurate to this community lmao

The founders relied on Emmerich de Vattel's text for the mesning.

Let's look directly at Emmerich de Vattel's text from "The Law of Nations" to clarify this:

In Book 1, Chapter 19, § 212, Vattel writes:

"The natives, or natural-born citizens, are those born in the country, of parents who are citizens. As the society cannot exist and perpetuate itself otherwise than by the children of the citizens, those children naturally follow the condition of their fathers and succeed to all their rights."

While this passage does emphasize the father's role, it mentions "parents" in the plural when defining natural-born citizens. This can be interpreted as requiring both parents to be citizens, but it also places particular importance on the father in terms of the child's legal status.

The focus on the father is typical of the time when Vattel wrote, reflecting societal norms where paternal lineage was often the primary determinant of citizenship and legal rights.

So, while Vattel's text does indeed highlight the father's condition, the broader context includes both parents as citizens when defining natural-born citizenship.

I would just use caution with dosage, it can be toxic in higher dosage for extended periods.