It's not for me.

My favorite type of Jew is messianic jew :). jewish christians

This is a misunderstanding. Sterilizing immunity refers to the type of immune response where the immune system completely eliminates a pathogen from the body, preventing the pathogen from replicating or establishing infection. With sterilizing immunity, the person not only avoids getting sick but also does not carry or spread the pathogen to others.

• I enjoy researching this stuff.
• That's fine, have them then possibly go on a modified "Low FODMAP" diet. In the end avoid highly processed foods, only shop on the outer edges of grocery stores, avoid seed oils.

Answer: Both Sides.

please use caution From a molecular biology of cancer standpoint this is not new information. The issue is how well does it translate to in vitro techniques? The pathway within living biology is more complicated than that of the. it works for target therapy for masses or lesions but not so well for stage 4b cancers unless you wanna play wakamole since this is essentially a double edged sword. It destroys the cells but triggers NF-κB, JAK/STAT, TNF-α, cox2 pathways which all then tells cancer cells remaining to proliferate. it's great to look into cancer research, but always dive deeper than what's shown, just like any other news, there is disinformation speed to hurt or muddy waters. be diligent.

I agree partially with you. The is false information always injected on the other side and on our side. Mudding the waters is just part of the paywar. If route looks clear, it's a trap.

• 1. Yes, individuals with chronic liver diseases like hepatitis C (HCV) might have an altered immune response, which could theoretically make them more vulnerable to certain adverse events from any vaccine
• 2. There have been reports of cases where individuals developed hepatitis after receiving the COVID-19 vaccine. Data from the Vaccine Adverse Event Reporting System (VAERS), shows a number of cases were reported following the COVID-19 vaccine between December 2020 and March 2022.
• 3. Yes. But first I do reccomend taking DAAs. Direct-acting antivirals (DAAs) for hepatitis C (HCV) are generally well-tolerated, with fewer side effects than older treatments like interferon and ribavirin. They also have a 95% success rate at clearing HCV.

• He can choose to taking the phytochemicals alongside the DAAs or just one or the other. It's up to him in the end.

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1. Phytochemicals and Their Mechanisms

1.1. Epigallocatechin Gallate (EGCG)

• Mechanisms in Combatting HCV:
  • Inhibits HCV NS3/4A protease and NS5B polymerase.
  • Suppresses viral replication.
• Mechanisms in Reversing Liver Damage:
  • Reduces oxidative stress.
  • Inhibits liver fibrosis by targeting fibrotic pathways.

1.2. Curcumin

• Mechanisms in Combatting HCV:
  • Inhibits HCV NS3/4A protease.
  • Modulates host immune response.
• Mechanisms in Reversing Liver Damage:
  • Reduces inflammation by suppressing pro-inflammatory cytokines.
  • Protects against oxidative damage.
  • Prevents liver fibrosis by inhibiting hepatic stellate cell activation.

1.3. Quercetin

• Mechanisms in Combatting HCV:
  • Interferes with HCV replication.
  • Affects cellular pathways involved in the viral life cycle.
• Mechanisms in Reversing Liver Damage:
  • Reduces oxidative stress.
  • Alleviates inflammation in the liver.

1.4. Silibinin / Silymarin

• Mechanisms in Combatting HCV:
  • Inhibits viral replication by targeting viral proteins.
• Mechanisms in Reversing Liver Damage:
  • Reduces oxidative stress.
  • Prevents liver fibrosis by blocking hepatic stellate cell activation.
  • Enhances liver regeneration.

1.5. Resveratrol

• Mechanisms in Combatting HCV:
  • Inhibits HCV replication by interfering with viral protein synthesis.
• Mechanisms in Reversing Liver Damage:
  • Reduces inflammation and fibrosis by modulating key signaling pathways.
  • Acts as an antioxidant to protect liver cells from damage.

1.6. Glycyrrhizin

• Mechanisms in Combatting HCV:
  • Modulates immune response to reduce viral replication.
• Mechanisms in Reversing Liver Damage:
  • Reduces inflammation and protects liver cells from damage.

1.7. Andrographolide

• Mechanisms in Combatting HCV:
  • Inhibits viral replication and reduces inflammation.
• Mechanisms in Reversing Liver Damage:
  • Reduces liver fibrosis.
  • Protects against oxidative stress and liver damage.

1.8. Phyllanthus amarus

• Mechanisms in Combatting HCV:
  • Exhibits antiviral activity by blocking viral replication.
• Mechanisms in Reversing Liver Damage:
  • Reduces liver inflammation and improves liver function.

1.9. Luteolin

• Mechanisms in Combatting HCV:
  • Inhibits viral replication and affects related cellular pathways.
• Mechanisms in Reversing Liver Damage:
  • Reduces inflammation and oxidative stress.
  • Prevents liver fibrosis.

1.10. Berberine

• Mechanisms in Combatting HCV:
  • Interferes with viral replication and reduces inflammation.
• Mechanisms in Reversing Liver Damage:
  • Reduces oxidative stress and inflammation.
  • Prevents liver fibrosis and improves liver function.

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Bioavailability Issues with Phytochemicals

Phytochemicals, despite their potential health benefits, often face significant challenges with bioavailability, which can limit their effectiveness in therapeutic applications. Bioavailability refers to the extent and rate at which the active ingredient or active moiety of a drug or supplement is absorbed and becomes available at the site of action. Here are typical issues of bioavailability associated with phytochemicals:

1. Poor Solubility:

   • Many phytochemicals are lipophilic (fat-loving) and poorly soluble in water. This limits their absorption in the gastrointestinal tract where the environment is predominantly aqueous.

2. Low Absorption Efficiency:

   • Even when phytochemicals are absorbed into the bloodstream, their ability to cross cellular membranes and reach systemic circulation can be limited. This is due to their large molecular size, poor permeability, or rapid metabolism.

3. First-Pass Metabolism:

   • Phytochemicals can be extensively metabolized by the liver and gut before reaching systemic circulation. This first-pass metabolism can significantly reduce their bioavailability.

4. Rapid Excretion:

   • Some phytochemicals are rapidly excreted from the body, reducing their time to exert therapeutic effects. This rapid clearance can be due to renal excretion or metabolism by the liver.

5. Instability:

   • Phytochemicals can be unstable and degrade quickly when exposed to environmental factors such as light, heat, and oxygen. This instability can further reduce their bioavailability.

6. Interaction with Food and Drugs:

   • Phytochemicals can interact with dietary components or medications, affecting their absorption and metabolism. For example, certain foods can inhibit or enhance the absorption of specific phytochemicals.

Liposomal and Nano Formulations for Enhancing Bioavailability

Liposomal and nano formulations are advanced delivery systems designed to overcome these bioavailability issues and enhance the therapeutic efficacy of phytochemicals.

1. Liposomal Formulations

• Structure and Function:

  • Liposomes are spherical vesicles composed of phospholipid bilayers that encapsulate phytochemicals. This lipid-based structure enhances the solubility of lipophilic compounds in an aqueous environment.

• Enhanced Absorption:

  • Liposomes can fuse with cell membranes, facilitating the direct delivery of encapsulated phytochemicals into cells. This improves absorption and bioavailability.

• Protection from Degradation:

  • Liposomes protect phytochemicals from degradation by encapsulating them in a lipid shell, which shields the active ingredients from environmental factors such as oxygen and light.

• Reduced First-Pass Metabolism:

  • Liposomal formulations can bypass some of the metabolic processes in the liver and gut, reducing first-pass metabolism and increasing the amount of phytochemical reaching systemic circulation.

2. Nano Formulations

• Structure and Function:

  • Nanoparticles are ultrafine particles with diameters in the nanometer range that can encapsulate or bind phytochemicals. They are designed to improve the solubility and stability of these compounds.

• Improved Cellular Uptake:

  • Nanoparticles can penetrate cellular membranes more effectively due to their small size. They can deliver phytochemicals directly into cells, enhancing their therapeutic effects.

• Controlled Release:

  • Nano formulations can provide controlled and sustained release of phytochemicals, which helps in maintaining therapeutic levels over extended periods and reduces the frequency of dosing.

• Enhanced Stability:

  • The encapsulation of phytochemicals in nanoparticles can protect them from degradation and extend their shelf life. This stability is crucial for maintaining the efficacy of the active compounds.

• Targeted Delivery:

  • Nanoparticles can be engineered to target specific tissues or cells, improving the precision of delivery and reducing potential side effects. This targeting can enhance the therapeutic efficacy.

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Suppliments to avoid

• Piperine this is in a lot of supplements be careful.
• Kava
• Pennyroyal Oil
• Comfrey
• Black Cohosh
• Chaparral
• Skullcap
• Valerian
• Aloe Vera

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Links to highly bioavailable supplements

I don't recommend taking all of these at once, If i had to choose it would be: Quercetin, Resveratrol, EGCG, Curcumin.

• Nano Curcumin: https://a.co/d/dxAqEPH Do not take in excess. Excessive curcumin may inhibit certain liver enzymes, leading to an accumulation of substances the liver typically detoxifies.

• Liposomal EGCG: https://a.co/d/3vJ2VzA Do not take in excess. High doses have been associated with liver toxicity and liver injury.

• Nano Quercetin: https://a.co/d/6C81D9k

• Nano Silymarin: https://a.co/d/fyQuxJn

• Nano Resveratrol: https://a.co/d/912GOvN

• Nano Andrographis: https://a.co/d/iXVpmuY

• Liposomal Luteolin: https://a.co/d/bcFdOh0

• Nano Berberine: https://a.co/d/2mkZgmh

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Lifestyle Changes

• Become Carnivore, if you cant handle that, do the Animal Diet, If you cant handle that at the very least go on to the Low FODMAP Diet.

... is this an ad? Are you a shill? This video is from voyager, which makes a bunch of fake content.

I personally have one of those outdated guns that don't have a 5g network access. It doesn't even have a digital screen.

So is section 230 going away?

• All I know is that #2 is a strawman. This issue is not that he used a fake rank, the issue is that he said he was in combat when he wasn't.

It's commendable that you're taking the initiative to review published research. However, it's important to recognize that individual articles may carry inherent biases. The gold standard for evaluating research data is through meta-analyses. Here is a meta-analysis that evaluates the effects of silymarin on ALT levels in patients with HCV:

• Meta-analysis on Silymarin and ALT Levels in HCV Patients

Unfortunately, the study found no significant difference in ALT levels between HCV patients treated with silymarin and those given a placebo.

To gain further insight, it may be useful to examine in vitro studies:

• In vitro Study 1
• In vitro Study 2

These publications suggest that the disparity between in vitro and in vivo results may be attributed to the low oral bioavailability of silymarin, which is estimated to be less than 5%, coupled with its hydrophobic nature:

• Oral Bioavailability Issues - Publication 1
• Oral Bioavailability Issues - Publication 2
• Oral Bioavailability Issues - Publication 3

Based on this data, while silymarin demonstrates antiviral activity in vitro, its low bioavailability significantly diminishes its effectiveness in vivo.

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To enhance the efficacy of silymarin, various formulation strategies can be considered:

• Nano Formulations: Approximately 50-70% bioavailability (Amazon Link)
• Silipide Phytosome Formulations: Approximately 20-40% bioavailability
• Liposomal Formulations: Approximately 30-50% bioavailability

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Let me know if you have any questions or need more information.

No problem. Please let me know anytime if you have questions on any of that or any thing else.

You are aware they aren't trying to act as though it's the oval office right?

Nano-curcumin, nano-egcg, nanoresveratrol. Take all 3 of these. Avoid seed oils and processed foods. And go get checked on what foods are inflammatory to you. Avoid those. You need to avoid inflammatory as much as you can. Somewhere said nicotine patches or gum helped them

You can always come back to me if you want more indepth info, or rational. but here you go:

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1. Fenbendazole:

• 888mg (2 pills) 3 times a week with lots of water.
• https://fenben.pro/product/fenbendazol-capsules-444-mg-180-units/
• Break the capsules into water and take it that way.

2. Nano curcumin:

• 3 times a day. 1 pill each time
• https://a.co/d/5pV679t
• break the pill directly into your mouth without water. (It tastes good no worries)

3. Liposomal EGCG

• 2 times a day with water.
• https://a.co/d/9fO0LMN
• take it out of the capsule take it with water.

4. Nano resveratrol

• take it 3 times a day
• https://a.co/d/8KeLoLT
• place under tongue for 1 minute then swallow.

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• results should take about 1 - 3 months to visually see cancer diminish.
• some formulations may not appear to mix with water unless you blend or mix them with an electronic mixer.
• behavioral changes could also improve outcomes, mainly avoiding ultra processed foods, avoiding seed oils, processed sugars, etc.
• again, just let me know if you have any questions in any of it, why take something, when, what does it do, how. Etc. I am here for you fren.

For those that want more clinical information, here is a quick write up I did on it.

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Intracellular Pathways Influenced by Ivermectin

• 1. Inhibition of the Wnt/β-Catenin Signaling Pathway: The Wnt/β-catenin pathway plays a critical role in cell proliferation and differentiation. Aberrant activation of this pathway is associated with various cancers. Ivermectin has been shown to inhibit this pathway, leading to reduced tumor growth and metastasis.
• 2. Modulation of mTOR Pathway: The mammalian target of rapamycin (mTOR) is a key regulator of cell growth and metabolism. Ivermectin can inhibit the mTOR pathway, which is often overactive in cancer cells, thereby reducing cell proliferation and promoting apoptosis.
• 3. Induction of Autophagy and Apoptosis: Ivermectin can induce autophagy, a process where cells degrade and recycle their components. This autophagic response can lead to apoptosis, particularly in cancer cells, where cellular stress and damage are prevalent. By promoting cell death in this manner, ivermectin can effectively reduce cancer cell viability.

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Inhibition of Glycolysis

Cancer cells often rely on glycolysis for energy production, a phenomenon known as the Warburg effect. Ivermectin has been shown to interfere with glycolysis by:

• 1. Targeting Key Glycolytic Enzymes: Ivermectin can inhibit enzymes involved in the glycolytic pathway, such as hexokinase and phosphofructokinase. By disrupting these enzymes, ivermectin impairs the energy production of cancer cells, making it difficult for them to sustain rapid growth.
• 2. Downregulation of Glucose Transporters: Ivermectin has been observed to reduce the expression of glucose transporters (GLUTs) on the cell surface. This reduction limits glucose uptake, further restricting the glycolytic capacity of cancer cells and leading to energy depletion.

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Overcoming Chemoresistance: Inhibition of P-glycoprotein (P-gp) Pumps

Chemoresistance is a significant challenge in cancer treatment, often mediated by P-glycoprotein (P-gp) pumps. These pumps actively expel chemotherapeutic agents from cancer cells, reducing their efficacy. Ivermectin's ability to inhibit P-gp pumps is crucial for overcoming this resistance:

• 1. Direct Inhibition of P-gp Activity: Ivermectin directly interacts with P-gp, reducing its drug efflux capacity. This inhibition allows chemotherapeutic agents to remain inside the cells at therapeutic concentrations, enhancing their cytotoxic effects.
• 2. Restoration of Drug Sensitivity: By inhibiting P-gp, ivermectin can restore sensitivity to previously resistant cancer drugs. This property is particularly valuable in cases where cancer cells have developed resistance to multiple drugs, often a result of overexpression of P-gp.
• 3. Synergistic Effects with Chemotherapeutic Agents: Ivermectin has been shown to work synergistically with certain chemotherapeutic agents, such as doxorubicin and vincristine, enhancing their efficacy by preventing drug expulsion from cancer cells. This combination therapy approach could lead to more effective treatment regimens with potentially lower doses of chemotherapeutic agents, reducing toxicity and side effects.

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Questions?

• if you want more information on this topic, phytochemicals, their pharmacokinetic properties, other intracellular routes of cancer etc. Or you just want some research on a particular subject around medicine done, Just let me know, I would be happy to help.

Really it depends on what concentrations have a clinical effect, and how long the cells need exposure.

1. Pharmacokinetics:

• Nicotine Gum: Delivers nicotine quickly through the lining of the mouth, causing rapid but short-lived increases in nicotine concentration. This leads to transient spikes in cellular nicotine levels, with periods of higher concentration followed by a rapid decline.

• Nicotine Patch: Provides a slow and steady release of nicotine through the skin, resulting in a stable and sustained increase in nicotine levels in the bloodstream. This steady delivery maintains a consistent cellular nicotine concentration over a prolonged period.

2. Cellular Implications:

• Nicotine Gum: The intermittent spikes in nicotine levels prevent prolonged receptor activation, reducing the risk of long-term receptor desensitization and cellular adaptation, You end up with peaks of high concentrations.

• Nicotine Patch: Continuous exposure to nicotine leads to sustained receptor activation, which can result in receptor desensitization or downregulation over time due to prolonged cellular exposure. You end up with steady but lower concentrations.

I actually don't mind people experimenting to help themselves. At the same time I just want to make sure that people do their due diligence in researching deeply into whatever care they plan to use. I go so far that recently, even this weekend, I called the manufacturers of a liposomal EGCG suppliment because I wanted them to send me their pharmacokinetic and clinical data to prove their technology before I purchase it. In fact, one such company last week, gave me lots of material, their patent data, clinical data, and was happy to create a document. They said I was the first client to ask for such data which to me is kind of unfortunate. More people should do research and not just accept something as true even if it seems like it falls onto our side.

Can I see the clinical data?

• Please be aware that in vitro experiments demonstrate the effects of a drug or compound in a controlled environment outside of a living organism, which does not account for the complex interactions that occur in vivo. Often, findings from in vitro studies do not directly correlate with in vivo outcomes.

• For example, nicotine is rapidly metabolized into its primary metabolite, cotinine, in the human body, with a half-life of approximately 2 hours. Thus, if you aim to achieve a particular clinical effect of nicotine on specific cells in the body at a desired concentration, it is crucial to consider its rapid metabolism and the subsequent downstream effects of this process.

Could I ask you a question about your beliefs? I am trinitarian, and in the Torah there is some passages that I cannot help but read them and see a multiplicity of the Person's of God. I can't even steelman it and would like to understand more deeply the modern Jewish interpretations.

It's okay if you aren't up to it, I was just curious

Oh, so you aren't jewish by blood you mean?Just by religion?

Which type? I was just researching different yehudi peoples last night.